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Table 1 Clinical characteristics and parameters

From: Increment of plasma glucose by exogenous glucagon is associated with present and future renal function in type 2 diabetes:a retrospective study from glucagon stimulation test

 

n = 209

Gender (male/female)

108 / 101

Age (years)

60.7

±

1.0

BMI (kg/m2)

27.5

±

0.4

Systolic blood pressure (mmHg)

116.6

±

0.9

Diastolic blood pressure (mmHg)

67.6

±

0.7

Diabetic duration (years)

13.0

±

0.8

HbA1c (%)

9.7

±

0.1

Glucose at 0 min (mg/dl)

122.2

±

1.6

Glucose at 6 min (mg/dl)

140.4

±

1.6

ΔGlucose (mg/dl)

18.2

±

0.5

Serum CPR at 0 min (ng/ml)

1.84

±

0.08

Serum CPR at 6 min (ng/ml)

3.56

±

0.14

ΔCPR (ng/ml)

1.72

±

0.07

AST (IU/l)

31.6

±

1.8

ALT (IU/l)

35.9

±

2.6

Albumin (g/dl)

3.97

±

0.03

Cholinesterase (IU/l)

340.4

±

5.5

Total Bilirubin (mg/dl)

0.80

±

0.02

PT-INR

0.99

±

0.01

Total Cholesterol (mg/dl)

186.5

±

2.7

Triglyceride (mg/dl)

146.1

±

6.3

HDL-Cholesterol (mg/dl)

44.1

±

0.9

LDL-Cholesterol (mg/dl)

116.7

±

2.3

Apolipoprotein A−1 (mg/dl)

124.1

±

1.5

Apolipoprotein B (mg/dl)

95.9

±

1.5

Apolipoprotein E (mg/dl)

4.5

±

0.1

Lipoprotein (a) (mg/dl)

20.7

±

1.7

Free Fatty Acid (mEq/l)

0.56

±

0.02

Remnant Like Particle Cholesterol (mg/dl)

5.37

±

0.35

Serum Creatinine (mg/dl)

0.76

±

0.02

Estimated GFR (ml/min/1.73m2)

82.4

±

2.3

30 and < 45, n (%)

24

(11.5)

45 and < 60, n (%)

23

(11.0)

60 and < 90, n (%)

86

(41.1)

90, n (%)

76

(36.4)

Serum Cystatin C (mg/dl)

0.90

±

0.02

Urinary Albumin (mg/gCr)

257.6

±

55.7

Urinary Albumin (mg/day)

256.0

±

50.0

Treatment

 Glucose lowering agents

  Insulin, n (%)

162

(77.5)

  Biguanides, n (%)

59

(28.2)

  Sulfonylureas, n (%)

27

(12.9)

  DPP-4 inhibitors, n (%)

118

(56.4)

  GLP-1 R agonists, n (%)

17

(8.1)

  Others, n (%)

43

(20.6)

Hypertension, n (%)

109

(52.2)

Antihypertensive agents in subjects with hypertension

  Angiotensin-converting enzyme inhibitors, n (%)

7

(6.4)

  Angiotensin receptor blockers, n (%)

79

(72.5)

  Calcium channel blockers, n (%)

72

(66.1)

  Diuretics, n (%)

33

(30.3)

  Alpha-blockers, n (%)

10

(9.2)

  Beta-blockers, n (%)

5

(4.6)

  1. The data are presented as means ± SEM. BMI Body mass index, CPR C-peptide immunoreactivity, AST Aspartate aminotransferase, ALT Alanine aminotransferase, PT-INR Prothrombin time-international normalized ratio, HDL High-density lipoprotein, LDL Low-density lipoprotein, GFR Glomerular filtration rate, DPP-4 Dipeptidyl peptidase-4, GLP-1 Glucagon-like peptide-1