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Table 3 Comparisons of thyroid nodule characteristics between the GH-secreting and NF pituitary adenoma groups

From: Evaluation of the thyroid characteristics of patients with growth hormone-secreting adenomas

Characteristics

Groups

NF (n = 21)

GH (n = 47)

χ 2

P

Single & multiple

Single

12 (57.1%)

9 (19.1%)

9.816

0.002*

Multiple

9 (42.9%)

38 (80.9%)

  

Total nodule

 

39

191

  

Morphology*

Solid

20 (51.3%)

98 (51.3%)

0.013

0.994

Mix

17 (43.6%)

84 (44.0%)

  

Cystic

2 (5.1%)

9 (4.7%)

  

Location

Right

21 (53.9%)

95 (49.7%)

5.917

0.052

Left

14 (35.9%)

91 (47.6%)

  

Isthmus

4 (10.3%)

5 (2.6%)

  

Echogenicity

Hypoechoic

25 (64.1%)

146 (76.4%)

9.972

0.019*

Isoechogenic

4 (10.3%)

27 (14.1%)

  

Hyperechoic

10 (25.6%)

16 (8.4%)

  

None

0 (0%)

2 (1.0%)

  

Echotexture

Homogeneous

25 (64.1%)

82 (42.9%)

5.835

0.016*

Heterogeneous

14 (35.9%)

109 (57.1%)

  

Margin

Regular

25 (64.1%)

144 (75.4%)

2.118

0.146

Irregular

14 (35.9%)

47 (24.6%)

  

Calcification

None

37 (94.9%)

177 (92.7%)

1.464

0.481

Micro

0 (0%)

6 (3.1%)

  

Macro

1 (5.1%)

8 (4.2%)

  

Blood vessel

None

6 (15.4%)

4 (2.1%)

15.156

0.001*

Rare

32 (82.1%)

169 (88.5%)

  

Rich

1 (2.6%)

18 (9.4%)

  
  1. Note: *P < 0.05