Skip to main content

Table 1 Patient characteristics

From: Investigating the risk of bone fractures in elderly patients with type 2 diabetes mellitus: a retrospective study

 

All Cases

No fractures

Fractures

P value

n = 2112

n = 2043

n = 69

 

Sex (male, %)

64.9

65.6

36.8

< 0.001

Age (years)

76.5 ± 7.1

76.4 ± 7.1

79.7 ± 7.6

0.002

BMI (kg/m2)

23.1 ± 4.1

23.1 ± 4.1

22.3 ± 5.0

0.9

HbA1c (%)

7.1 ± 1.2

7.1 ± 1.2

6.8 ± 1.4

0.92

eGFR (mL/min/1.73m2)

54.5 ± 22.1

54.3 ± 22.1

62.1 ± 23.9

0.02

Patients with fractures, n (%)

69 (3.3%)

0 (0)

69 (100)

< 0.001

Number of drugs being administered at the time of hospitalization

7.7 ± 3.8

7.7 ± 3.8

7.7 ± 3.3

0.52

Patients not using hypoglycemic agent, n (%)

700 (33.1)

674 (33.0)

26 (36.8)

0.62

Glinides, n (%)

0

0

0

SGLT2 inhibitors, n (%)

8 (0.4)

8 (0.4)

0

0.7

TZD, n (%)

148 (7.0)

137 (6.7)

11 (15.9)

0.03

αGI, n (%)

200 (9.5)

194 (9.5)

6 (8.7)

0.74

BG, n (%)

407 (19.3)

398 (19.5)

9 (13.0)

0.17

SU, n (%)

542 (25.7)

527 (25.8)

15 (21.7)

0.3

DPP-4 inhibitors, n (%)

904 (42.8)

877 (42.9)

27 (39.1)

0.45

GLP-1 receptor agonists, n (%)

39 (1.8)

36 (1.8)

3 (4.3)

0.11

Insulin, n (%)

440 (20.8)

425 (20.8)

15 (21.7)

0.66

  1. Mean ± S.D., BMI (body mass index), HbA1c (hemoglobin A1c), eGFR (estimated glomerular filtration rate), SGLT2 inhibitors (sodium glucose cotransporter 2 inhibitors), TZD (thiazolidines), αGI (α-glucosidase inhibitors), BG (biguanides), SU (sulfonylureas), DPP-4 inhibitors (dipeptidyl peptidase 4 inhibitors), GLP-1 receptor agonist (glucagon-like peptide-1 receptor agonist)