Table 4 The process of refinement of the tool and the performance (measured using area under the receiver operating curve (AUROC)) of each version compared to a clinicians assessment of lifetime risk of T2DM
Risk factors Core | Risk factors Plus one | AUROC | |
|---|---|---|---|
Tool | OO, ST | WC, AN, FLD, PCOS, PDM, MS, FH, ETH, WG04, SI, SGA, BF, OP | 0.74 (0.71, 0.78) |
Removing variables | |||
Tool 1 | OO, ST | - AN | 0.74 (0.71, 0.78) |
Tool 2 | OO, ST | - AN, FLD | 0.74 (0.71, 0.78) |
Tool 3 | OO, ST | - AN, FLD, PCOS | 0.74 (0.71, 0.78) |
Tool 4 | OO, ST | - AN, FLD, PCOS, SI | 0.74 (0.71, 0.78) |
Tool 5 | OO, ST | - AN, FLD, PCOS, SI, MS | 0.74 (0.71, 0.78) |
Tool 6 | OO, ST | - AN, FLD, PCOS, SI, MS, FH | 0.74 (0.71, 0.78) |
Tool 7 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM | 0.74 (0.71, 0.78) |
Tool 8 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH | 0.75 (0.71, 0.78) |
Tool 9 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH, OP | 0.75 (0.71, 0.78) |
Tool 10 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH, OP, BF | 0.74 (0.71, 0.78) |
Tool 11 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH, OP, BF, SGA | 0.74 (0.71, 0.77) |
Tool 12 | OO, ST | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH, OP, BF, SGA, WG04 | 0.73 (0.69, 0.76) |
Collaboration requested refinements | |||
Tool 13 | OO | - AN, FLD, PCOS, SI, MS, FH, PDM, ETH, OP, BF, SGA | 0.80 (0.76, 0.83) |
Tool 14 | OO | Tool 13 + OP, BF | 0.81 (0.78, 0.84) |
Tool 15 | OO | Tool 14 – WG04 | 0.81 (0.78, 0.84) |
Tool 16 | OO | Tool 15 + FH or 2nd degree family history diabetes (FH2) | 0.81 (0.78, 0.83) |
Tool 17 | OO | Tool 16 + SI | 0.80 (0.77, 0.83) |
Tool 18 | OO | Tool 17 + ST | 0.80 (0.78, 0.83) |
Tool 19 | OO | Tool 18 + low physical activity | 0.80 (0.78, 0.83) |
Tool 20 (final tool) | OO | Tool 19 + low fruit and veg | 0.80 (0.77, 0.83) |
Tool 21 | OO | Tool 20 + AN | 0.80 (0.77, 0.83) |