NGT (n = 68) | IGR (n = 112) | T2DM (n = 174) | P-value NGT vs IGR | P-value NGT vs T2DM | P-value IGR vs T2DM | |
---|---|---|---|---|---|---|
Male | 42 | 66 | 92 | |||
Female | 26 | 46 | 82 | |||
Age (years) | 53 ± 10 | 53 ± 9 | 55 ± 10 | 1.000 | 0.163 | 0.087 |
BMI (kg/m2) | 23.88 ± 2.59 | 25.91 ± 3.21 | 24.52 ± 3.08 | < 0.001 | 0.131 | 0.001 |
Waist circumference (cm) | 82.09 ± 8.47 | 92.60 ± 10.53 | 90.43 ± 7.68 | < 0.001 | < 0.001 | 0.045 |
WHR | 0.83 ± 0.07 | 0.93 ± 0.06 | 0.91 ± 0.05 | < 0.001 | < 0.001 | 0.003 |
SBP (mmHg) | 128.54 ± 15.71 | 132.94 ± 12.99 | 135.96 ± 16.37 | 0.044 | 0.002 | 0.101 |
DBP (mmHg) | 76.46 ± 11.55 | 81.47 ± 8.77 | 81.43 ± 9.36 | 0.001 | 0.001 | 0.971 |
TG (mmol/L) | 1.38 ± 0.71 | 1.95 ± 1.02 | 1.78 ± 0.74 | < 0.001 | 0.001 | 0.104 |
TC (mmol/L) | 4.99 ± 0.99 | 5.82 ± 0.86 | 5.48 ± 1.10 | < 0.001 | 0.002 | 0.006 |
HDL-C (mmol/L) | 1.35 ± 0.39 | 1.27 ± 0.24 | 1.30 ± 0.26 | 0.090 | 0.248 | 0.327 |
LDL-C (mmol/L) | 2.16 ± 0.75 | 3.21 ± 0.83 | 3.02 ± 0.82 | < 0.001 | < 0.001 | 0.058 |
FBG (mmol/L) | 5.04 ± 0.57 | 6.08 ± 0.70 | 8.37 ± 1.56 | < 0.001 | < 0.001 | < 0.001 |
HbA1c (%) | 5.52 ± 0.44 | 6.33 ± 0.40 | 9.76 ± 2.79 | < 0.001 | < 0.001 | < 0.001 |
FINS (mU/mL) | 10.50 ± 4.85 | 11.61 ± 5.90 | 8.14 ± 5.22 | 0.193 | 0.001 | < 0.001 |
C-peptide (μg/L) | 3.10 ± 0.86 | 3.23 ± 1.49 | 2.12 ± 0.67 | 0.513 | < 0.001 | < 0.001 |
HOMA-IR* | 2.42 ± 0.48 | 2.85 ± 0.53 | 3.00 ± 0.67 | < 0.001 | < 0.001 | 0.046 |
HOMA-β* | 4.78 ± 0.46 | 4.05 ± 0.33 | 3.72 ± 0.52 | < 0.001 | < 0.001 | < 0.001 |
QUICKI * | 0.375 ± 0.02 | 0.356 ± 0.01 | 0.336 ± 0.01 | < 0.001 | < 0.001 | < 0.001 |
Matsuda index | 14.92 ± 2.86 | 8.07 ± 1.47 | 5.87 ± 1.31 | < 0.001 | < 0.001 | < 0.001 |