Table 3 Comparison of endocrinopathy in different series
From: Endocrine Manifestations in POEMS Syndrome: a case report and literature review
Characteristics | Nakanishi et al.[15], N = 102 (1984) No.(%)of patients | Soubrier et al.,[18] N = 25 (1994) No.(%)of patients | Dispenzieri et al.,[1] N = 99 (2002) No.(%)of patients | Gandhi et al.,[4] N = 64 (2007) No.(%)of patients | Hu et al. [19], N = 23 (2017) No.(%)of patients | |
|---|---|---|---|---|---|---|
Any endocrine abnormality | NR | NR | 66/99(66) | 54/64(84) | 22/23(96) | |
Adrenal axis abnormality | NR | NR | 16/35(46) | 6/9(67) | 10/17(59) | |
Hyperprolactinemia | NR | 4/17(24) | 5/25(20) | 10/35(29) | 9/15(60) | |
Diabetes mellitus or glucose intolerance | 26/93(28) | 9/22(41) | 3/99(3) | 24/50(48) | 5/23(22) | |
Hypothyroidism | 5/21(24) | 10/22(45) | 26/99(26) | 28/48(58) | 13/22(59) | |
Hypocalcemia | NR | NR | 1/4(25) | 14/51(27) | 3/10(30) | |
Gonad related dysfunction | Hypogonadism | NR | 9/19(47) | 55/99(55) | 26/33(79) | 7/18(39) |
Erectile dysfunction (males) | 39/50(78) | 13/13(100) | 44/63(71) | 23/38(61) | NR | |
Gynecomastia or galactorrhea (males) | 43/63(68) | 10/13(77) | 17/63(27) | 10/38(26) | NR | |
Multiple endocrine abnormalities | NR | NR | NR | 29/54(54) | NR | |