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Table 1 Maternal characteristics in the first pregnancy (N = 142)

From: Frequency and risk factors for recurrent gestational diabetes mellitus in primiparous women: a case control study

Variables

Recurrent GDM

N = 78

Primary GDM

N = 64

Unadjusted OR

(95% CI)

p value

Age (years)

30.0 ± 0.3

29.7 ± 0.4

1.05 (0.93–1.17)

0.442

Prepregnancy weight (kg)a

58.2 ± 1.2

58.8 ± 1.3

0.99 (0.95–1.04)

0.736

Prepregnancy BMI (kg/m2) a

22.8 ± 0.5

22.2 ± 0.4

1.07 (0.94–1.22)

0.320

Gestational weight gain (kg) b

11.7 ± 0.8

12.4 ± 0.6

0.97 (0.88–1.07)

0.510

Educational attainment (years)

 ≤12

7 (9.0)

6 (9.4)

1.02 (0.32–3.23)

0.790

 13–16

54 (69.2)

47 (73.4)

Ref

 ≥17

17 (21.8)

11 (17.2)

1.35 (0.57–3.16)

Family history of first-degree diabetes

20 (25.6)

11 (17.2)

1.66 (0.73–3.79)

0.228

Insulin treatment

4 (5.1)

1 (1.6)

3.41 (0.37–31.26)

0.279

Conception by ART

5 (6.4)

2 (3.1)

2.12 (0.40–11.33)

0.378

Delivery by Cesarean Section

32 (41.0)

23 (35.9)

1.24 (0.63–2.45)

0.536

Birth weight (g)

3264 ± 55

3300 ± 47

1.00 (0.99–1.01)

0.624

Male baby

34 (43.6)

27 (42.2)

1.06 (0.54–2.07)

0.867

Biochemical parameters in first-trimester (weeks)

13.3 ± 0.2

13.3 ± 0.3

  

Fasting plasma glucose (mmol/L)

4.48 ± 0.05

4.66 ± 0.05

0.38 (0.17–0.88)

0.024*

Uric acid (umol/L)

226 ± 5

214 ± 5

1.01 (0.99–1.02)

0.108

Cholesterol (mmol/L)

5.01 ± 0.09

4.86 ± 0.11

1.28 (0.84–1.95)

0.250

Triglyceride (mmol/L)

1.68 ± 0.09

1.40 ± 0.07

1.94 (1.06–3.54)

0.031*

75-g OGTT in second-trimester (weeks)

26.4 ± 0.3

26.6 ± 0.4

  

Fasting (mmol/L)

4.62 ± 0.07

4.51 ± 0.07

1.40 (0.77–2.52)

0.269

1 h (mmol/L)

10.44 ± 0.17

9.82 ± 0.18

1.34 (1.05–1.71)

0.018*

2 h (mmol/L)

8.67 ± 0.17

8.55 ± 0.20

1.05 (0.84–1.31)

0.653

HbA1c (%) c

5.4 ± 0.1

5.3 ± 0.1

3.00 (1.03–8.78)

0.045*

[HbA1c (mmol/mol)]

36 ± 1

34 ± 1

1.11 (1.00–1.22)

0.045*

  1. Variables are presented with mean ± standard error (SE) unless number (percentage)
  2. GDM gestational diabetes mellitus, OR odds ratio, CI confidence interval, BMI body mass index, ART assisted reproductive technology, OGTT oral glucose tolerance test, HbA1c glycated hemoglobin
  3. a Prepregnancy weight and BMI: 32.4% missing;
  4. b Gestational weight gain: 41.5% missing;
  5. c HbA1c: 26.1% missing