Variables | Recurrent GDM N = 78 | Primary GDM N = 64 | Unadjusted OR (95% CI) | p value |
---|---|---|---|---|
Age (years) | 30.0 ± 0.3 | 29.7 ± 0.4 | 1.05 (0.93–1.17) | 0.442 |
Prepregnancy weight (kg)a | 58.2 ± 1.2 | 58.8 ± 1.3 | 0.99 (0.95–1.04) | 0.736 |
Prepregnancy BMI (kg/m2) a | 22.8 ± 0.5 | 22.2 ± 0.4 | 1.07 (0.94–1.22) | 0.320 |
Gestational weight gain (kg) b | 11.7 ± 0.8 | 12.4 ± 0.6 | 0.97 (0.88–1.07) | 0.510 |
Educational attainment (years) | ||||
 ≤12 | 7 (9.0) | 6 (9.4) | 1.02 (0.32–3.23) | 0.790 |
 13–16 | 54 (69.2) | 47 (73.4) | Ref | |
 ≥17 | 17 (21.8) | 11 (17.2) | 1.35 (0.57–3.16) | |
Family history of first-degree diabetes | 20 (25.6) | 11 (17.2) | 1.66 (0.73–3.79) | 0.228 |
Insulin treatment | 4 (5.1) | 1 (1.6) | 3.41 (0.37–31.26) | 0.279 |
Conception by ART | 5 (6.4) | 2 (3.1) | 2.12 (0.40–11.33) | 0.378 |
Delivery by Cesarean Section | 32 (41.0) | 23 (35.9) | 1.24 (0.63–2.45) | 0.536 |
Birth weight (g) | 3264 ± 55 | 3300 ± 47 | 1.00 (0.99–1.01) | 0.624 |
Male baby | 34 (43.6) | 27 (42.2) | 1.06 (0.54–2.07) | 0.867 |
Biochemical parameters in first-trimester (weeks) | 13.3 ± 0.2 | 13.3 ± 0.3 |  |  |
Fasting plasma glucose (mmol/L) | 4.48 ± 0.05 | 4.66 ± 0.05 | 0.38 (0.17–0.88) | 0.024* |
Uric acid (umol/L) | 226 ± 5 | 214 ± 5 | 1.01 (0.99–1.02) | 0.108 |
Cholesterol (mmol/L) | 5.01 ± 0.09 | 4.86 ± 0.11 | 1.28 (0.84–1.95) | 0.250 |
Triglyceride (mmol/L) | 1.68 ± 0.09 | 1.40 ± 0.07 | 1.94 (1.06–3.54) | 0.031* |
75-g OGTT in second-trimester (weeks) | 26.4 ± 0.3 | 26.6 ± 0.4 |  |  |
Fasting (mmol/L) | 4.62 ± 0.07 | 4.51 ± 0.07 | 1.40 (0.77–2.52) | 0.269 |
1 h (mmol/L) | 10.44 ± 0.17 | 9.82 ± 0.18 | 1.34 (1.05–1.71) | 0.018* |
2 h (mmol/L) | 8.67 ± 0.17 | 8.55 ± 0.20 | 1.05 (0.84–1.31) | 0.653 |
HbA1c (%) c | 5.4 ± 0.1 | 5.3 ± 0.1 | 3.00 (1.03–8.78) | 0.045* |
[HbA1c (mmol/mol)] | 36 ± 1 | 34 ± 1 | 1.11 (1.00–1.22) | 0.045* |