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Table 2 Characteristics of new users of glucagon-like peptide-1 analogues

From: Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

All Data Sources

2008

2009

2010

2011

2012

2013

2014

Total

N

587

753

1 158

2 035

1 160

950

714

7 357

Women, %

55.2

52.7

51.5

49.3

50.3

46.5

46.2

50.0

Mean age

57.9

58.2

58.7

58.0

57.6

58.6

57.2

58.1

Age bands, %

18-44

8.5

9.2

8.4

10.9

10.9

11.7

12.9

10.4

45-64

65.6

63.7

63.5

62.4

63.9

57.2

61.1

62.4

65-84

25.9

26.8

28.0

26.1

24.8

29.3

25.9

26.7

85+

 

0.3

0.2

0.6

0.3

1.9

0.1

0.5

Prior antidiabetic treatmentsa, %

No antidiabetics

3.7

4.8

6.6

16.5

11.6

18.6

16.9

12.3

Insulin with/without non-insulin antidiabetics

23.0

25.4

22.3

20.6

25.7

23.5

19.0

22.6

Non-insulin antidiabetic monotherapy

14.3

16.3

19.9

28.2

30.0

32.4

37.3

26.3

≥1 non-insulin antidiabetic

58.9

53.5

51.2

34.7

32.7

25.5

26.8

38.9

Patients with 1 year follow-up, %

99.8

99.7

99.9

99.7

99.3

98.9

0.0

89.9

Patients with 1 year follow-up, N

586

751

1 157

2 029

1 152

939

-

6 614

Following antidiabetic treatmentsb, %

≥1 additional dispensing of a GLP1a

84.0

84.0

82.2

82.7

82.1

74.8

-

81.6

Persistent users of incretins (any)

54.3

60.6

60.1

65.1

62.2

53.3

-

60.6

Switchers to a DPP4i

3.4

3.7

6.2

5.7

8.1

4.7

-

5.6

≥1 additional dispensing of non-incretin antidiabetic

91.6

91.1

86.3

86.1

84.7

79.9

-

86.1

≥1 additional dispensing of any antidiabetic

97.1

96.7

94.5

93.2

93.1

88.2

-

93.5

  1. GLP1a glucagon-like peptide-1 analogues, DPP4i dipeptidyl peptidase-4 inhibitors
  2. a≥1 dispensing within 365 days preceding the index GLP1a dispensing
  3. bDugs dispensed during 365 days following the index GLP1a dispensing were considered
  4. Persistent use: no gaps ≥90 days between the end of the duration of a dispensing and the following one
  5. Switchers: ≥1 dispensing of a DPP4i