| |
Random glucose category (in mmol/L)
|
|---|
|
Model
|
< 4.3
|
4.3 - < 5.3
|
5.3 - < 5.8
|
5.8 - < 6.8
|
6.8 - < 7.8
|
7.8 - < 11.1
|
≥ 11.1
|
|---|
|
a) adjusted for fasting timea
|
1.96 (0.87–4.43)
|
ref.
|
1.16 (0.89–1.51)
|
1.22 (0.92–1.60)
|
1.46 (0.89–2.39)
|
2.10 (1.28–3.42)
|
4.99 (2.33–10.73)
|
|
b) excluding fasting time < 2 hb
|
2.07 (0.85–5.03)
|
ref.
|
1.14 (0.87–1.50)
|
1.18 (0.89–1.57)
|
1.43 (0.85–2.41)
|
2.20 (1.25–3.86)
|
4.38 (2.01–9.58)
|
|
c) adjusted for HbA1cc
|
1.96 (0.86–4.44)
|
ref.
|
1.17 (0.90–1.51)
|
1.21 (0.91–1.60)
|
1.35 (0.83–2.20)
|
1.82 (1.09–3.03)
|
3.46 (1.49–8.04)
|
|
d) excluding HbA1c ≥ 6.5%d
|
1.73 (0.73–4.09)
|
ref.
|
1.12 (0.85–1.48)
|
1.23 (0.92–1.63)
|
1.08 (0.54–2.13)
|
2.46 (1.50–4.03)
|
–
|
|
e) excluding FU time ≤ 2 yearse
|
2.10 (0.87–5.06)
|
ref.
|
1.12 (0.85–1.46)
|
1.11 (0.82–1.48)
|
1.30 (0.77–2.19)
|
1.97 (1.21–3.21)
|
3.72 (1.51–9.19)
|
|
f) multiple imputationf
|
1.68 (0.92–3.07)
|
ref.
|
1.12 (0.88–1.41)
|
1.25 (0.98–1.59)
|
1.81 (1.17–2.80)
|
1.94 (1.26–3.01)
|
2.96 (1.48–5.92)
|
-
Models with adjustment as in model 4 with additional adjustment for fasting time in a) and HbA
1c
in c)
-
a
fasting time with five categories (< 2, 2 - < 4, 4 - < 8, 8 - < 12 and ≥ 12 h)
-
b
n = 5579 (428 cases, 5151 non-cases)
-
c
HbA
1c
with five categories (< 5.0, 5.0- < 5.7, 5.7- < 6.5, ≥ 6.5%)
- d n = 5718 (386 cases, 5332 non-cases), no participant with random glucose ≥ 11.1 mmol/L
-
e
n = 5912 (415 cases, 5497 non-cases)
- f n = 6570 (551 cases, 6061 non-cases, 138 missings), missings were replaced in the source population using multiple imputation by fully conditional specification
