Skip to main content

Table 3 Adverse pregnancy outcomes according to maternal TSH concentration in the first trimester

From: Effect of mildly elevated thyroid-stimulating hormone during the first trimester on adverse pregnancy outcomes

Pregnancy outcomes

Normal

(n = 1532), n (%)

eTSH (2.5–4 mIU/L) (n = 142), n (%)

χ2

P

Mother

 IUGR

12 (0.8)

1 (0.7)

0.00

1.00

 GDM

163 (10.6)

12 (8.5)

0.67

0.42

 Gestational hypertension/preeclampsia

25 (1.6)

1 (0.7)

0.25

0.62

 PROM

394 (25.7)

30 (21.1)

1.45

0.23

 Placental abruption

14 (0.9)

1 (0.7)

0.00

1.00

 Placenta previa

15 (1.0)

0 (0.0)

0.52

0.47

 Premature delivery (< 37 weeks)

60 (3.9)

3 (2.1)

0.72

0.40

 PPH

50 (3.3)

5 (3.5)

0.03

0.87

 Delivery method (assisted vaginal delivery or cesarean section)

95 (25.9)

7 (23.3)

0.10

0.76

Newborn

 LBW

38 (2.5)

4 (2.8)

0.00

1.00

 SGA

36 (2.3)

3 (2.1)

0.00

1.00

 LGA

236 (15.4)

21 (14.8)

0.04

0.84

 Apgar score ≤ 7 at 1 or 5 min

27 (1.8)

0 (0.0)

1.55

0.21

  1. TSH thyroid-stimulating hormone, eTSH elevated thyroid-stimulating hormone, IUGR intrauterine growth restriction, GDM gestational diabetes mellitus, PROM premature rupture of membranes, PPH postpartum hemorrhage, LBW low birth weight, SGA small for gestational age, LGA large for gestational age