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Table 2 Characteristics of the study participants divided by first-trimester TSH concentrationa

From: Effect of mildly elevated thyroid-stimulating hormone during the first trimester on adverse pregnancy outcomes

Characteristics Normal (n = 1532) eTSH (2.5–4 mIU/L) (n = 142) P
Maternal age (years) 30 (27–34) 29 (28–32) 0.35
Pregestational BMI (kg/m2) 20.03 (18.83–21.68) 19.32 (±1.91) 0.01
Gestational age at delivery (weeks) 39.29 (38.57–40.00) 39.14 (38.57–40.00) 0.83
Postpartum hemorrhage volume (ml) 305 (255–380) 317 (260–380) 0.41
Neonatal birth weight (kg) 3.20 (2.95–3.50) 3.27 (±0.41) 0.05
TSH (mIU/L) 1.06 (0.67–1.54) 3.06 (2.76–3.40) < 0.001
FT4 (pmol/L) 16.46 (±3.11) 15.82 (±2.74) 0.02
Blood glucose on 75-g OGTT (mmol/L)
 0 h 4.12 (3.94–4.36) 4.13 (3.92–4.31) 0.42
 1 h 7.30 (6.16–8.46) 6.64 (5.70–7.86) < 0.001
 2 h 6.45 (5.64–7.36) 6.31 (5.58–7.01) 0.12
  1. aValues are mean (SD) or median (interquartile range)
  2. TSH thyroid-stimulating hormone, eTSH elevated thyroid-stimulating hormone, BMI body mass index, FT4 free thyroxine 4, OGTT oral glucose tolerance test