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Table 2 Characteristics of the study participants divided by first-trimester TSH concentrationa

From: Effect of mildly elevated thyroid-stimulating hormone during the first trimester on adverse pregnancy outcomes

Characteristics

Normal

(n = 1532)

eTSH (2.5–4 mIU/L)

(n = 142)

P

Maternal age (years)

30 (27–34)

29 (28–32)

0.35

Pregestational BMI (kg/m2)

20.03 (18.83–21.68)

19.32 (±1.91)

0.01

Gestational age at delivery (weeks)

39.29 (38.57–40.00)

39.14 (38.57–40.00)

0.83

Postpartum hemorrhage volume (ml)

305 (255–380)

317 (260–380)

0.41

Neonatal birth weight (kg)

3.20 (2.95–3.50)

3.27 (±0.41)

0.05

TSH (mIU/L)

1.06 (0.67–1.54)

3.06 (2.76–3.40)

< 0.001

FT4 (pmol/L)

16.46 (±3.11)

15.82 (±2.74)

0.02

Blood glucose on 75-g OGTT (mmol/L)

 0 h

4.12 (3.94–4.36)

4.13 (3.92–4.31)

0.42

 1 h

7.30 (6.16–8.46)

6.64 (5.70–7.86)

< 0.001

 2 h

6.45 (5.64–7.36)

6.31 (5.58–7.01)

0.12

  1. aValues are mean (SD) or median (interquartile range)
  2. TSH thyroid-stimulating hormone, eTSH elevated thyroid-stimulating hormone, BMI body mass index, FT4 free thyroxine 4, OGTT oral glucose tolerance test