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Table 4 Associations of XbaI genotypes with various clinical characteristics

From: Estrogen receptor 1 gene polymorphisms are associated with metabolic syndrome in postmenopausal women in China

Variables

AA (n = 74)

AG (n = 154)

GG (n = 76)

Age (years)

62.14 ± 4.24

63.24 ± 4.85

63.11 ± 3.75

BMI (kg/m2)

22.97 ± 2.99

23.98 ± 3.40*

24.71 ± 3.18*

Waist circumference (cm)

84.26 ± 5.36

84.92 ± 5.13

86.07 ± 4.96*

FBG (mM)

4.95 ± 0.88

5.21 ± 1.41*

5.70 ± 1.10*#

HbA1C (%)

5.89 ± 1.00

5.94 ± 1.05

6.09 ± 0.98

Systolic blood pressure (mmHg)

132.31 ± 14.39

134.15 ± 13.96

139.05 ± 14.12*#

Diastolic blood

pressure (mmHg)

79.95 ± 11.96

81.14 ± 11.39

85.86 ± 10.69*#

Triglycerides (mM)

1.84 ± 0.92

2.08 ± 1.20*

2.38 ± 1.16*

Total cholesterol (mM)

4.29 ± 1.20

4.72 ± 0.83*

5.53 ± 1.12*#

HDL-C (mM)

1.25 ± 0.26

1.15 ± 0.21*

1.06 ± 0.20*#

LDL-C (mM)

2.74 ± 0.64

2.83 ± 0.67

3.39 ± 0.83*#

NAFLD (%)

28 (37.8)

70 (45.5)

45 (59.2)*

Fasting serum

insulin (μIU/mL)

11.15 ± 5.68

11.54 ± 6.23

12.54 ± 8.31

Estradiol (pg/ml)

26.82 ± 6.99

24.66 ± 7.48

24.49 ± 7.67

HOMA-IR

2.47 ± 1.32

2.72 ± 1.77*

3.20 ± 1.70*

  1. Measurement data are mean ± SD, and were assessed by one way ANOVA with post-hoc SNK test
  2. *Significant difference from patients harboring AA (p < 0.05)
  3. #Significant difference from patients harboring AG (p < 0.05). Enumeration count data were described as rate, and assessed by the chi-square test