Table 2 Laboratory characteristics according to the shape of the glucose curve
Shape of the glucose curve | p-value | ||
|---|---|---|---|
Monophasic | Biphasic | ||
N | 97 | 24 | – |
FPG – mmol/L | 5.38 ± 0.63 | 5.15 ± 0.44 | 0.044ab |
30minPG – mmol/L | 9.22 [8.19–10.53] | 7.83 [6.76–9.04] | 0.001ab |
1hPG – mmol/L | 9.83 [8.36–11.64] | 6.03 [5.33–8.71] | < 0.001ab |
90minPG – mmol/L | 9.16 ± 2.40 | 6.60 ± 1.87 | < 0.001ab |
2hPG – mmol/L | 8.11 [5.92–9.39] | 6.33 [5.07–8.49] | 0.028ab |
Glucose AUC – mmol/L.h | 17.55 ± 3.49 | 13.79 ± 2.99 | < 0.001a |
HbA1c - % | 5.81 ± 0.63 | 5.74 ± 0.51 | 0.630 |
Fasting serum insulin – pmol/L | 66.18 [45.15–100.47] | 44.07 [32.10–67.65] | 0.016ab |
2-h serum insulin – pmol/L | 476.70 [284.07–1017.51] | 301.50 [148.98–470.16] | 0.012ab |
Gutt index | 3.22 [2.43–4.12] | 3.95 [3.06–5.29] | 0.006ab |
Insulinogenic index | 0.91 [0.53–1.48] | 1.48 [0.70–2.95] | 0.017ab |
Disposition index | 2.99 [1.76–5.82] | 6.42 [3.16–11.55] | 0.002ab |
C-Peptide – nmol/L | 0.76 [0.43–0.96] | 0.43 [0.38–0.70] | 0.027ab |
Glucagon – ng/L | 332.50 [200.00–640.00] | 600.00 [220.00–780.00] | 0.115 |
Total cholesterol – mmol/L | 5.41 ± 1.14 | 5.41 ± 1.10 | 0.990 |
HDL cholesterol – mmol/L | 1.22 [1.01–1.37] | 1.53 [1.23–1.76] | < 0.001ab |
Triglycerides – mmol/L | 1.54 [1.04–2.14] | 1.29 [0.80–1.67] | 0.106 |
hs-CRP – nmol/L | 25.67 [11.90–67.83] | 25.71 [13.48–63.29] | 0.930 |
Adiponectin – μg/mL | 11.93 [9.06–15.74] | 15.42 [11.24–21.20] | 0.018ab |
PP – pg/mL | 194.20 [103.65–392.15] | 464.45 [204.90–808.15] | 0.049ab |