Table 4 Anthropometric measurements before and after treatment in PCOS patients
Parameters | Saxagliptin | Saxagliptin + Metformin | Metformin | ||||||
|---|---|---|---|---|---|---|---|---|---|
Baseline | Treatment | Δ | Baseline | Treatment | Δ | Baseline | Treatment | Δ | |
Weight, kg | 70.4 (63.7 to 77.1) | 69.4 (62.8 to 76.1)** | −1.0 (− 1.3 to − 0.6)** | 69.3 (64.6 to 74.1) | 67.0 (62.4 to 71.6)** | − 2.4 (− 2.8 to 2.0)** | 67.9 (63.6 to 72.2) | 65.1 (61.0 to 69.3)** | −2.8 (− 3.4 to − 2.2)** |
BMI, kg/m2 | 27.2 (24.94 to 29.46) | 26.68 (24.51 to 28.85)** | −0.52 (− 0.82 to − 0.22)** | 26.38 (24.66 to 28.1) | 25.46 (23.79 to 27.13)** | −0.92 (− 1.08 to − 0.75)** | 26.4 (24.63 to 28.18) | 25.32 (23.63 to 27.02)** | −1.09 (− 1.32 to − 0.85)** |
WC, cm | 86.8 (81.2 to 92.4) | 84.3 (79.1 to 89.5)** | − 2.5 (− 3.1 to − 1.9) | 84.7 (80.0 to 89.4) | 81.5 (77.1 to 85.8)** | − 3.2 (− 3.9 to − 2.6) | 82.8 (78.9 to 86.6) | 79.9 (76.4 to 83.3) ** | − 2.9 (− 3.5 to − 2.4) |
WHR | 0.88 ± 0.08 | 0.86 ± 0.08** | − 0.02 ± 0.02 | 0.86 ± 0.06 | 0.83 ± 0.05** | − 0.03 ± 0.02 | 0.85 ± 0.06 | 0.83 ± 0.05** | −0.02 ± 0.01 |
FAT% | 36.13 (32.74 to 39.53) | 33.89 (30.89 to 36.88)** | −2.25 (− 2.98 to − 1.52)* | 35.12 (32.19 to 38.05) | 31.59 (29.01 to 34.16)** | −3.53 (− 4.36 to − 2.71)* | 33.6 (31.21 to 35.98) | 30.5 (28.34 to 32.67) ** | −3.2 (− 3.81 to − 2.59)* |