Table 2 Clinical characteristics of patients with adrenal crisis at admission separated by different pathophysiological mechanisms
| Â | Â | Primary AI | Central AI | Others | ALL |
|---|---|---|---|---|---|
|  |  | (N = 23) | (N = 136) | (N = 345) | (n = 504) |
Age (years) | Median (IQR) | 59 (36–73) | 65 (49–74) | 73 (62–82) | 71 (59–80) |
Male | Â | 9 (39.1) | 73 (53.7) | 173 (50.1) | 255 (50.6) |
Indication for hospital admissiona | Adrenal insufficiencyb | 6 (26.1) | 26 (19.1) | 50 (14.5) | 82 (16.3) |
Pituitary disease | 3 (13.0) | 69 (50.7) | 2 (0.6) | 74 (14.7) | |
Cancer | 3 (13.0) | 2 (1.5) | 69 (20.0) | 74 (14.7) | |
Infection | 2 (8.7) | 10 (7.4) | 44 (12.8) | 56 (11.1) | |
Cardiovascular disease | 0 (0.0) | 2 (1.5) | 19 (5.5) | 21 (4.2) | |
Sepsis | 1 (4.3) | 3 (2.2) | 13 (3.8) | 17 (3.4) | |
Adrenal tumor | 0 (0.0) | 0 (0.0) | 10 (2.9) | 10 (2.0) | |
AI-related clinical symptomc | 2 (8.7) | 12 (8.8) | 44 (12.8) | 58 (11.5) | |
Comorbidityd | Cardiovascular disease | 7 (30.4) | 40 (29.4) | 109 (31.6) | 156 (31.0) |
Infection | 5 (21.7) | 26 (19.1) | 65 (18.8) | 96 (19.0) | |
Diabetes | 1 (4.3) | 22 (16.2) | 57 (16.5) | 80 (15.9) | |
Cancer | 1 (4.3) | 0 (0.0) | 66 (19.1) | 67 (13.3) | |
Hypothyroidism | 2 (8.7) | 27 (19.9) | 24 (7.0) | 53 (10.5) | |
Autoimmune disease | 0 (0.0) | 1 (0.7) | 32 (9.3) | 33 (6.5) | |
Peptic ulcer | 2 (8.7) | 9 (6.6) | 21 (6.1) | 32 (6.3) | |
COPD or asthma | 1 (4.3) | 4 (2.9) | 21 (6.1) | 26 (5.2) | |
Renal failure | 0 (0.0) | 5 (3.7) | 21 (6.1) | 26 (5.2) | |
Therapeutic GC regimen | HC | 18 (78.3) | 107 (78.7) | 203 (58.8) | 328 (65.3) |
mPSL | 4 (17.4) | 14 (10.3) | 56 (16.2) | 74 (14.7) | |
DEX | 1 (4.3) | 6 (4.4) | 37 (10.7) | 44 (8.7) | |
Others | 0 (0.0) | 9 (6.6) | 49 (14.2) | 58 (11.3) |