Table 1 Patient characteristics at baseline
Preoperative medical therapy (n = 81) | Primary surgery (n = 277) | P | |
|---|---|---|---|
M/F | 41/40 | 125/152 | 0.38 |
Age of onset (y) | 34.8 ± 11.4 | 34.6 ± 11.7 | 0.86 |
Age of diagnosis (y) | 40.3 ± 11.9 | 40.1 ± 12.1 | 0.89 |
Mean basal GH (μg/L) | 44.47 ± 16.13 | 48.17 ± 17.52 | 0.68 |
Mean IGF-1 (μg/L) | 841.27 ± 313.26 | 889.50 ± 306.21 | 0.31 |
Microadenoma (%) | 10 (12.3) | 29 (10.5) | 0.63 |
Macroadenoma (%) | 71 (87.7) | 248 (89.5) | 0.63 |
aTumor invasion (Knosp) | 67 | 135 | 0.161 |
Knosp 0 (%) | 21 (31.3) | 49 (36.3) | |
Knosp 1 (%) | 6 (9.0) | 12 (8.9) | |
Knosp 2 (%) | 19 (28.4) | 42 (31.1) | |
Knosp 3 (%) | 14 (20.9) | 29 (21.5) | |
Knosp 4 (%) | 7 (10.4) | 3 (2.2) |