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Fig. 4 | BMC Endocrine Disorders

Fig. 4

From: Multihormonal pituitary adenoma concomitant with Pit-1 and Tpit lineage cells causing acromegaly associated with subclinical Cushing’s disease: a case report

Fig. 4

Immunofluorescent analysis using (a) tumor tissue and (b) its primary culture. (a) ACTH-stained (red) cells existed in the majority of GH-stained (green) cells. White arrow indicates an ACTH-stained cell (× 400). (b) The expression of Pit-1 (green) decreased in the nuclei of the cells with their cytosols stained by ACTH compared to GH-stained cells. White arrow indicates an ACTH-stained cell in the cytoplasm. Yellow arrow indicates a Pit-1-stained cell in the nucleus (× 400)

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