Skip to main content

Advertisement

Table 1 Subject characteristics of the complete two groups, unadjusted

From: Metabolic characteristics of individuals at a high risk of type 2 diabetes – a comparative cross-sectional study

  Non-FDR FDR p
N 73 200  
Sex male (%) 33 (45.2) 81 (40.5) 0.576
Age (years) 36.68 (7.99) 40.05 (7.16) 0.001
Weight (kg) 83.93 (14.86) 75.98 (12.95) <0.001
BMI (kg/m2) 27.22 (3.91) 25.14 (3.47) <0.001
Fat percent (%) 27.87 (9.24) 26.42 (8.09) 0.218
DI (mL/mol/min) 3.63 (3.56) 2.78 (2.88) 0.108
Waist circumference (cm) 90.37 (10.64) 88.39 (10.20) 0.169
WHR 0.85 (0.08) 0.86 (0.08) 0.334
Diastolic blood pressure (mmHg) 77.53 (8.98) 73.64 (9.75) 0.003
Systolic blood pressure (mmHg) 121.19 (14.50) 115.99 (12.22) 0.004
High heredity for T2D (%) 0 (0.0) 7 (3.6) <0.001
High heredity for CHD (%) 9 (13.0) 76 (29.6) 0.001
Currently smoking (%) 7 (10.2) 22 (11.3) 0.877
Exercise >4 times per week (%) 41 (57.7) 68 (35.2) 0.008
High stress level (%) 9 (13.0) 34 (17.7) 0.010
Serum adiponectin (ng/mL) 8295.29 (3551.68) 9064.92 (4436.85) 0.233
Serum triglycerides (mmol/L) 0.91 (0.48) 1.03 (0.54) 0.131
Serum HDL (mmol/L) 1.42 (0.32) 1.55 (0.38) 0.031
Serum cholesterol (mmol/L) 4.66 (0.86) 4.82 (0.89) 0.185
Serum LDL (mmol/L) 3.78 (0.80) 2.84 (0.84) <0.001
Serum creatinine (μmol/L) 74.91 (12.45) 85.86 (16.81) <0.001
OGTT fasting plasma glucose (mmol/L) 4.74 (0.36) 4.81 (0.42) 0.165
OGTT plasma glucose 30 min (mmol/L) 7.55 (1.54) 7.99 (1.54) 0.044
OGTT plasma glucose 60 min (mmol/L) 6.90 (1.90) 7.76 (2.12) 0.003
OGTT plasma glucose 90 min (mmol/L) 5.87 (1.51) 6.95 (1.89) <0.001
OGTT plasma glucose 120 min (mmol/L) 5.56 (1.37) 6.12 (1.59) 0.010
OGTT fasting serum insulin (pmol/L) 58.77 (36.19) 49.20 (29.30) 0.048
OGTT serum insulin 30 min (pmol/L) 489.05 (336.05) 412.03 (245.01) 0.068
OGTT serum insulin 60 min (pmol/L) 454.58 (297.68) 431.35 (261.66) 0.572
OGTT serum insulin 90 min (pmol/L) 336.85 (257.46) 396.38 (297.55) 0.162
OGTT serum insulin 120 min (pmol/L) 305.38 (267.73) 318.93 (288.16) 0.746
HOMA-β (%) 150.53 (81.27) 118.88 (63.90) 0.003
IGI (pmol/mmol) 194.70 (250.13) 136.18 (144.01) 0.044
M-value (GIR/kg/min: g/kg/min) 11.94 (4.49) 13.00 (4.16) 0.085
M/I 0.02 (0.01) 0.02 (0.01) 0.083
OGTT insulin AUC (pmol/L/120 min 44,235.77 (28,021.78) 43,030.71 (25,137.08) 0.764
OGTT glucose AUC (mmol/L/120 min 763.75 (149.28) 844.66 (166.09) <0.001
HOMA-IR 12.58 (2.27) 10.69 (0.19) 0.092
  1. Data are, for categorical variables, given as frequencies (percentage) and for continuous variables as mean (standard deviation). P-values have been obtained as explained in the method section. FDR first-degree relatives, WHR waist-hip ratio, T2D type 2 diabetes, CHD coronary heart disease, HDL high-density lipoprotein, LDL low-density lipoprotein, HOMA-β homeostasis assessment model-beta, IGI insulinogenic index, DI disposition index, M and M/I insulin resistance level, GIR glucose infusion rate