Table 3 Multiple Logistic Regression Analysis for determinants of autoimmunity in T2DM patients
Variable | Unadjusted Odds ratio 95% CI | p-value | Adjusted Odds ratio 95% CI | p-value |
|---|---|---|---|---|
Age | ||||
For each 10 years older | 1.00 (0.88–1.15) | 0.96 | - | - |
Gender | ||||
Female | 4.45 (2.17–9.15) | <0.0001 | 3.16 (1.46–6.87) | 0.004 |
Male | 1.00 | |||
Thyroid function | ||||
Euthyroidism | 1.00 | - | ||
Clinical hyperthyroidism | 1.98 (1.04–3.04) | <0.0001 | 1.41 (1.20–1.98) | <0.0001 |
Clinical hypothyroidism | 2.21 (2.11–3.41) | <0.0001 | 1.61 (1.35–2.23) | <0.0001 |
Subclinical hyperthyroidism | 2.5 (2.19–2.90) | <0.0001 | 2.19 (1.70–2.58) | <0.0001 |
Subclinical hypothyroidism | 5.0 (4.60–5.50) | <0.0001 | 3.57 (2.74–3.82) | <0.0001 |
Glycaemic state | ||||
For every 1% increase in HbA1c | 1.83 (1.53–2.19) | <0.0001 | 1.46 (1.23–1.73) | <0.0001 |
Cholesterol status | ||||
For 1 mmol increase in total Cholesterol | 1.55 (1.28–1.87) | <0.0001 | 1.44 (1.17–1.77) | 0.01 |