Table 5 Values of indexes describing the diagnostic efficacy of particular UMRFs and their sets in UC and FL nodules
Sonographic feature | Category of FNA | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
UC | FL | |||||||||
SEN [%] | SPC [%] | PPV [%] | NPV [%] | % of nodules | SEN [%] | SPC [%] | PPV [%] | NPV [%] | % of nodules | |
1 – hypoechogenicity | 86.0 | 51.0 | 46.7 | 87.9 | 61.3 | 73.1 | 31.1 | 8.5 | 94.8 | 69.3 |
2 - solid echostructure | 94.0 | 42.5 | 45.0 | 93.4 | 69.7 | 92.3 | 23.3 | 9.6 | 97.2 | 77.9 |
3 – (1 & 2)- hypoechogenicity of solid nodule | 80.0 | 68.5 | 55.9 | 87.3 | 47.7 | 65.4 | 45.6 | 9.5 | 93.8 | 55.3 |
4 - taller-than-wide shape | 30.0 | 86.5 | 53.6 | 71.3 | 18.7 | 23.1 | 88.2 | 14.6 | 97.8 | 12.7 |
5 - pathological vascularization | 19.0 | 93.0 | 57.6 | 69.7 | 11.0 | 26.9 | 78.7 | 10.0 | 92.5 | 21.7 |
6 - suspicious margin | 31.0 | 85.5 | 51.7 | 71.3 | 20.0 | 3.8 | 93.6 | 5.0 | 91.7 | 6.2 |
7 – calcifications (micro or macro) | 28.0 | 86.5 | 50.9 | 70.6 | 18.3 | 34.6 | 88.5 | 20.9 | 93.9 | 13.4 |
7a – microcalcifications | 13.0 | 98.0 | 76.5 | 69.3 | 5.7 | 7.7 | 95.3 | 12.5 | 98.7 | 5.0 |
7b – isolated macrocalcifications | 15.0 | 88.5 | 39.5 | 67.6 | 12.7 | 26.9 | 93.2 | 25.9 | 93.6 | 8.4 |
Sets of sonographic features | ||||||||||
A1 - >2 UMRFs of: 1, 2, 4, 5, 6, 7a | 55.0 | 85.0 | 64.7 | 79.1 | 28.3 | 30.8 | 76.0 | 10.1 | 92.6 | 24.5 |
A2 - >2 UMRFs of: 1, 2, 4, 5, 6, 7 | 63.0 | 80.0 | 61.1 | 81.2 | 34.3 | 46.2 | 73.3 | 13.2 | 93.9 | 28.3 |
B1 - >2 UMRFs of: 1, 2, 4, 6, 7a (TIRADS) | 46.0 | 87.5 | 64.8 | 76.4 | 23.7 | 23.1 | 87.5 | 14.0 | 92.8 | 13.4 |
B2 - >2 UMRFs of: 1, 2, 4, 6, 7 | 53.0 | 83.5 | 61.6 | 78.0 | 28.7 | 38.5 | 84.5 | 17.9 | 94.0 | 17.4 |
C - 3 with 4 or 6 or 7a (ATA) | 46.0 | 87.0 | 63.9 | 76.3 | 24.0 | 19.2 | 87.8 | 12.2 | 92.5 | 12.7 |
D - >2 UMRFs of: 1, 2, 4, 7 | 43.0 | 90.0 | 66.2 | 75.9 | 21.0 | 38.5 | 87.5 | 21.3 | 94.2 | 14.6 |