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Table 2 Cox regression models for the prediction of incident CHD by BMI categories and mediators, by gender

From: Gender-modulated risk of coronary heart disease, diabetes and coronary mortality among Turks for three major risk factors, and residual adiposity risk

 

Total

Men

Women

HR

95 % CI

HR

95 % CI

HR

95 % CI

404/2153a

185/1011a

219/1142a

Sex, female

0.93

0.73; 1.18

    

Age, 11 years

1.78

1.64; 1.96

1.82

1.59; 2.08

1.76

1.56; 2.00

Current vs. never smoking

1.60

1.24; 2.07

1.58

1.11; 2.25

1.65

1.13; 2.42

Former vs. never smoking

1.28

0.91; 1.79

1.25

0.83; 1. 09

1.32

0.67; 2.58

Overweight

1.40

1.05; 1.85

1.44

1.01; 2.05

1.40

0.87; 2.24

Obesity

2.24

1.68; 2.99

2.00

1.34; 3.00

2.48

1.59; 3.87

Model 1

 Sex, female

0.83

0.68; 1.02

    

 Age, 11 years

1.57

1.43; 1.73

1.56

1.34; 1.78

1.57

1.37; 1.78

 Overweight

1.18

0.89; 1.57

1.17

0.82; 1.67

1.19

0.74; 1.92

 Obesity

1.61

1.20; 2.17

1.37

0.89; 2.10

1.79

1.14; 2.80

 Systolic BP, 25 mmHg

1.37

1.24; 1.51

1.52

1.27; 1.82

1.31

1.17; 1.48

Model 2

 Sex, female

0.87

0.71; 1.07

    

 Age, 11 years

1.64

1.51; 1.80

1.71

1.49; 1.96

1.61

1.40; 1.84

 Overweight

1.26

0.95; 1.67

1.31

0.92; 1.86

1.27

0.79; 2.03

 Obesity

1.87

1.41; 2.50

1.69

1.12; 2.55

2.10

1.35; 3.25

 Total cholesterol, 40 mg/dl

1.23

1.11; 1.37

1.25

1.07; 1.45

1.23

1.07; 1.42

 Fasting glucose, 25 mg/dl

1.12

1.04; 1.20

1.02

0.92; 1.13

1.20

1.05; 1.32

Model 3

399/2098a

183/987a

216/1111a

 Sex, female

0.92

0.72; 1.18

    

 Age, 11 years

1.62

1.45; 1.78

1.61

1.39; 1.86

1.61

1.38; 1.84

 Current vs. never smoking

1.67

1.28; 2.17

1.68

1.17; 2.42

1.61

1.09; 2.38

 Former vs. never smoking

1.30

0.93; 1.83

1.23

0.82; 1.72

1.47

0.75; 2.90

 Overweight

1.19

0.90; 1.59

1.19

0.82; 1.72

1.31

0.81; 2.11

 Obesity

1.56

1.15; 2.12

1.30

0.83; 2.04

1.90

1.20; 3.02

 LDL-cholesterol, 32 mg/dl

1.14

1.04; 1.26

1.13

0.98; 1.31

1.16

1.02; 1.32

 HDL-cholesterol, 12 mg/dl

0.89

0.80; 0.99

0.96

0.82; 1.12

0.83

0.72; 0.96

 Fasting glucose, 25 mg/dl

1.12

1.04; 1.21

1.05

0.92; 1.19

1.20

1.08; 1.32

 Systolic BP, 25 mmHg

1.38

1.25; 1.52

1.52

1.27; 1.82

1.32

1.17; 1.49

  1. Overweight and obesity prevailed in 45.6 and 18.9 % in men, in 35.2 and 44.4 % in women
  2. Referent in adiposity categories was BMI ≤25 kg/m2
  3. aIncident cases/whole sample Diabetes prevailed in 100 (46 M/54 W) participants at baseline
  4. Bold numbers denote significant values