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Table 1 Characteristics of the girls with early puberty at presentation

From: Familial early puberty: presentation and inheritance pattern in 139 families

  PP (n = 68) AP (n = 48) Total (n = 116)
n m ± SD n m ± SD n m ± SD
Age at onset, years 66 6.5 ± 1.8 48 8.6 ± 0.6 114 7.4 ± 1.8
Age at evaluation, years 66 7.4 ± 1.9 47 9.4 ± 1.1 113 8.2 ± 1.9
Height, SDS 65 2.1 ± 1.3 47 1.2 ± 1.6 112 1.7 ± 1.5
BMI, SDS 65 1.1 ± 1.2 47 0.7 ± 1.5 112 0.9 ± 1.4
BA advance, years 61 1.2 ± 1.1 36 0.7 ± 1.4 97 1 ± 1.2
Tanner breast 66 2.7 ± 0.7 44 2.8 ± 0.9 110 2.8 ± 0.9
Tanner pubic hair 65 2.1 ± 1.1 42 2.4 ± 1.1 107 2.3 ± 1.1
Age at M mothers, years 66 11.7 ± 1.5 47 11.4 ± 1.6 113 11.6 ± 1.5
Age at M, years 12 10.9 ± 1.8 12 10.7 ± 2 24 10.8 ± 1.9
Uterus length, mm 50 36.5 ± 9 34 37.2 ± 11.5 84 36.8 ± 10
LH peak, IU/L 63 12.2 ± 18.7 33 12 ± 11.5 96 12.1 ± 16.5
FSH peak, IU/L 63 11 ± 5.1 33 9.8 ± 3.4 96 10.6 ± 4.6
LH/FSH peak ratio 63 1 ± 1.1 33 1.2 ± 1 96 1.07 ± 1.1
Estradiol, pg/mL 64 11.5 ± 18 39 12.3 ± 12.3 96 11.8 ± 16
GnRH analog treatment 68 16 46 6 114 22 (19,3 %)
  1. PP Central precocious puberty, AP Advanced puberty, M menstruation