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Table 1 Application of clinical data sources in the model base cases

From: Cost-effectiveness of tolvaptan for the treatment of hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion in Sweden

 

Population modelled

Parameter

General SIADH

SCLC

Pneumonia

Population characteristics

HN Registry and ART

HN Registry and ART

HN Registry and ART

[Na+] correction

HN Registry and SALT I & II

HN Registry and SALT I & II

HN Registry and SALT I & II

Duration of tolvaptan treatment

HN Registry

Expert clinical opinion

Expert clinical opinion

HRQL change

SALT I & II

SALT I & II

SALT I & II

Length of inpatient stay

SALT I & II

SALT I & II

SALT I & II

Inpatient mortality

ART

ART

ART

Readmission

ART

ART

ART

Long-term mortality

Swedish life-tables

ART

Swedish life-tables

  1. Abbreviations: ART the Assessment of epidemiology, patient characteristics and outcomes Related To patients with hyponatraemia/SIADH in Sweden, HN hyponatraemia, HRQL health related quality of life, SALT the Study of Ascending Levels of Tolvaptan in Hyponatremia, SCLC small cell lung cancer, SIADH syndrome of inappropriate antidiuretic hormone secretion