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Table 3 Distribution of vascular invasion, local infiltration, differentiation grading and Ki-67 LI in relation to primary site (absolute number and % of patients)

From: Results of a prospective multicenter neuroendocrine tumor registry reporting on clinicopathologic characteristics of Greek patients

Clinicopathologic features

Head &Necka

Bronchial

GEP

Pheochromocytoma

Unknown Primary

Total

N = 44

N = 16

N = 156

N = 6

N = 24

Vascular invasion

13 (28.2)

5 (10.8)

23 (50.0)

2 (4.3)

3 (6.5)

46 (100.0)

Local infiltration

22 (24.4)

6 (6.6)

55 (61.1)

2 (2.2)

5 (5.5)

90 (100.0)

Differentiation grading

      

G1

22 (16.6)

10 (7.5)

84 (63.6)

4 (3.0)

12 (9.0)

132 (100.0)

G2

18 (24.6)

6 (8.2)

42 (57.5)

2 (2.7)

5 (6.8)

73 (100.0)

G3

1 (4.7)

0 (0)

17 (80.9)

0 (0)

3 (14.2)

21 (100.0)

Ki-67 labelling index

      

Ki-67 ≤ 2

34 (20.4)

13 (7.8)

104 (62.6)

5 (3.0)

10 (6.0)

166 (100.0)

Ki-67 3-20

3 (5.3)

3 (5.3)

39 (69.6)

1 (1.7)

10 (17.8)

56 (100.0)

Ki-67 > 20

0 (0)

0 (0)

3 (50.0)

0 (0)

3 (50.0)

6 (100.0)

  1. aincludes 41 MTC and 3 paragangliomas