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Table 7 IGF-I/IGFBP3 ratioSDS variables and their correlations with gain in height outcomes

From: Growth hormone (GH) dose-dependent IGF-I response relates to pubertal height gain

ITT

Pubertal gain in heightSDS

Total gain in heightSDS

Prepubertal gain in heightSDS

IGF-I/IGFBP3 Ratio SDS

n

r

p

r

p

r

p

At GH start

71

−0,16

 

−0,37

0,001

−0,31

0,009

RatioSDS1st year after GH start

76

0,09

 

0,01

 

−0,08

 

∆RatioSDS1st year after GH start

63

0,28

0,026

0,42

0,001

0,24

0,061

RatioSDS Prepubertal level

100

0,03

 

−0,09

 

−0,10

 

Last pre-pubertal

90

0,08

 

0,01

 

−0,06

 

Study start

104

−0,02

 

−0,19

0,048

−0,16

0,095

1st year after study start

100

0,16

 

−0,11

   

∆RatioSDS1st year after study start

100

0,16

 

0,08

   

RatioSDS Pubertal level

104

0,23

0,021

−0,19

0,048

  

∆RatioSDS Pubertal level after study start

104

0,22

0,022

0,04

   

Before study stop

104

0,07

 

−0,14

   

After study stop

64

0,15

 

0,05

   
  1. Δ change IGF-I/IGFBP3 Ratio, IGF-I insulin-like growth factor I, IGFBP3 IGF-binding protein 3, SDS standard deviation score