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Table 1 Patient characteristics

From: Morning blood pressure surge and target organ damage in newly diagnosed type 2 diabetic patients: a cross sectional study

 

Patients with diabetes

Controls

P-value

Sex, n (Male/female)

97 (50/47)

97 (50/47)

-

Age (years)

58.5 ± 9.9

58.3 ± 9.8

-

Diabetes duration (years) (median, (25th;75 th)

1.8; 0.7; 3.2

-

-

Smoking, n (Current/previous/never)

21 / 36 / 39

21 / 32 / 44

0.77

Statin use, n (Yes/no)

74/22

18/79

<0.001

Antihypertensive treatment, n (Yes/no)

60/36

23/74

<0.001

 RAAS-inhibitors, n

48

11

 

 Calcium-antagonists, n

14

9

 

 Diuretics, n

39

10

 

β-blockers, n

9

7

 

BMI (kg/m2)

30.1 ± 4.8

26.1 ± 4.1

<0.001

HbA1c %

6.5 ± 0.6

5.6 ± 0.3

<0.001

HbA1c mmol/mol

48 ± 17

38 ± 20

<0.001

Total cholesterol (mg/dL)

79.2 ± 14.4

100.8 ± 18.0

<0.001

 LDL-cholesterol (mg/dL)

41.4 ± 12.6

59.4 ± 18.0

<0.001

 HDL-cholesterol (mg/dL)

25.2 ± 5.4

30.6 ± 10.8

<0.001

Triglycerides (mg/dL) (Median, 25th and 75th)

25.2; 19.8; 34.2

21.6; 16.2; 28.8

<0.01

Office measurements (mmHg)

   

 Systolic BP

125.6 ± 11.9

132.2 ± 15.7

<0.05

 Diastolic BP

78.8 ± 7.9

84.0 ± 10.5

<0.01

 Heart rate

65.9 ± 9.6

62.2 ± 10.7

<0.05

24-h ABPM (mmHg)

   

 Systolic BP

125.3 ± 10.8

124.2 ± 12.4

0.49

 Diastolic BP

74.0 ± 7.5

75.3 ± 7.4

0.21

 Heart rate

73.3 ± 9.5

68.3 ± 8.9

<0.001

 Daytime ABPM (mmHg)

   

   Systolic BP

130.6 ± 11.1

130.5 ± 13.3

0.97

   Diastolic BP

78.2 ± 8.0

79.9 ± 8.2

0.12

   Heart rate

76.7 ± 10.1

71.8 ± 9.8

<0.01

 Nighttime ABPM (mmHg)

   

   Systolic BP

114.9 ± 11.7

112.0 ± 12.0

0.08

   Diastolic BP

65.8 ± 7.7

66.3 ± 7.4

0.62

   Heart rate

66.6 ± 9.7

61.5 ± 8.8

<0.001

Pulse wave velocity (m/s)

9.3 ± 2.0

8.0 ± 1.6

<0.001

Urine albumine/creatinine (mg/mmol)

   

 (Median, (25th;75 th))

0.31 (0.21; 0.67)

0.23 (0.15; 0.40)

<0.01

Breteler score, n (0/1/2)

52 / 32 / 10

51 / 32 / 13

0.83

  1. Data are presented as n, mean ± SD, or median (interquartile range)
  2. Abbreviations: BMI Body Mass Index, LDL Low Density Lipoprotein, HDL High Density Lipoprotein, BP Blood Pressure, ABPM Ambulatory Blood Pressure Monitoring