Patients with diabetes | Controls | P-value | |
---|---|---|---|
Sex, n (Male/female) | 97 (50/47) | 97 (50/47) | - |
Age (years) | 58.5 ± 9.9 | 58.3 ± 9.8 | - |
Diabetes duration (years) (median, (25th;75 th) | 1.8; 0.7; 3.2 | - | - |
Smoking, n (Current/previous/never) | 21 / 36 / 39 | 21 / 32 / 44 | 0.77 |
Statin use, n (Yes/no) | 74/22 | 18/79 | <0.001 |
Antihypertensive treatment, n (Yes/no) | 60/36 | 23/74 | <0.001 |
RAAS-inhibitors, n | 48 | 11 | |
Calcium-antagonists, n | 14 | 9 | |
Diuretics, n | 39 | 10 | |
β-blockers, n | 9 | 7 | |
BMI (kg/m2) | 30.1 ± 4.8 | 26.1 ± 4.1 | <0.001 |
HbA1c % | 6.5 ± 0.6 | 5.6 ± 0.3 | <0.001 |
HbA1c mmol/mol | 48 ± 17 | 38 ± 20 | <0.001 |
Total cholesterol (mg/dL) | 79.2 ± 14.4 | 100.8 ± 18.0 | <0.001 |
LDL-cholesterol (mg/dL) | 41.4 ± 12.6 | 59.4 ± 18.0 | <0.001 |
HDL-cholesterol (mg/dL) | 25.2 ± 5.4 | 30.6 ± 10.8 | <0.001 |
Triglycerides (mg/dL) (Median, 25th and 75th) | 25.2; 19.8; 34.2 | 21.6; 16.2; 28.8 | <0.01 |
Office measurements (mmHg) | |||
Systolic BP | 125.6 ± 11.9 | 132.2 ± 15.7 | <0.05 |
Diastolic BP | 78.8 ± 7.9 | 84.0 ± 10.5 | <0.01 |
Heart rate | 65.9 ± 9.6 | 62.2 ± 10.7 | <0.05 |
24-h ABPM (mmHg) | |||
Systolic BP | 125.3 ± 10.8 | 124.2 ± 12.4 | 0.49 |
Diastolic BP | 74.0 ± 7.5 | 75.3 ± 7.4 | 0.21 |
Heart rate | 73.3 ± 9.5 | 68.3 ± 8.9 | <0.001 |
Daytime ABPM (mmHg) | |||
Systolic BP | 130.6 ± 11.1 | 130.5 ± 13.3 | 0.97 |
Diastolic BP | 78.2 ± 8.0 | 79.9 ± 8.2 | 0.12 |
Heart rate | 76.7 ± 10.1 | 71.8 ± 9.8 | <0.01 |
Nighttime ABPM (mmHg) | |||
Systolic BP | 114.9 ± 11.7 | 112.0 ± 12.0 | 0.08 |
Diastolic BP | 65.8 ± 7.7 | 66.3 ± 7.4 | 0.62 |
Heart rate | 66.6 ± 9.7 | 61.5 ± 8.8 | <0.001 |
Pulse wave velocity (m/s) | 9.3 ± 2.0 | 8.0 ± 1.6 | <0.001 |
Urine albumine/creatinine (mg/mmol) | |||
(Median, (25th;75 th)) | 0.31 (0.21; 0.67) | 0.23 (0.15; 0.40) | <0.01 |
Breteler score, n (0/1/2) | 52 / 32 / 10 | 51 / 32 / 13 | 0.83 |