| Total (N = 4017) | 100 mg (n = 2625) | 300 mg (n = 1392) | 100 mg vs 300 mg P value |
---|---|---|---|---|
Age, mean (SD) | 55.6 (9.8) | 55.8 (9.8) | 55.2 (9.7) | 0.039 |
Female gender, n (%) | 1727 (43) | 1136 (43) | 591 (42) | 0.618 |
Geographic region, n (%) | Â | Â | Â | Â |
 Northeast | 313 (8) | 225 (9) | 88 (6) | 0.011 |
 Midwest | 823 (20) | 585 (22) | 238 (17) | <0.001 |
 South | 2463 (61) | 1561 (59) | 902 (65) | <0.001 |
 West | 418 (10) | 254 (10) | 164 (12) | 0.038 |
Insurance type, n (%) | Â | Â | Â | Â |
 Commercial | 3542 (88) | 2315 (88) | 1227 (88) | 0.967 |
 Medicare Advantage | 475 (12) | 310 (12) | 165 (12) | 0.967 |
Race, n (%)a | Â | Â | Â | Â |
 White | 2758 (69) | 1809 (69) | 949 (68) | 0.631 |
 African American | 517 (13) | 350 (13) | 167 (12) | 0.229 |
 Hispanic | 438 (11) | 272 (10) | 166 (12) | 0.130 |
 Asian | 69 (2) | 50 (2) | 19 (1) | 0.210 |
 Other | 64 (2) | 37 (1) | 27 (2) | 0.202 |
 Unknown/missing | 171 (4) | 107 (4) | 64 (5) | 0.436 |
Baseline DCSI (continuous), mean (SD) | 0.85 (1.3) | 0.86 (1.3) | 0.83 (1.3) | 0.460 |
DCSI complications, n (%) | Â | Â | Â | Â |
 Neuropathy | 741 (18) | 477 (18) | 264 (19) | 0.537 |
 Cardiovascular | 677 (17) | 445 (17) | 232 (17) | 0.818 |
 Nephropathy | 394 (10) | 270 (10) | 124 (9) | 0.162 |
 Retinopathy | 363 (9) | 251 (10) | 112 (8) | 0.111 |
 Peripheral vascular disease | 252 (6) | 168 (6) | 84 (6) | 0.649 |
 Cerebrovascular | 129 (3) | 81 (3) | 48 (3) | 0.535 |
 Metabolic | 39 (1) | 22 (1) | 17 (1) | 0.239 |
No DCSI complications | 2306 (57) | 1502 (57) | 804 (58) | 0.742 |
Baseline concomitant oral anti-hyperglycemic agents count (excluding canagliflozin), mean (SD) | 2.26 (1.1) | 2.28 (1.1) | 2.22 (1.1) | 0.100 |
Prescribing provider type, n (%) | Â | Â | Â | Â |
 Primary care | 2100 (52) | 1352 (52) | 748 (54) | 0.178 |
 Endocrinology | 1103 (27) | 742 (28) | 361 (26) | 0.115 |
 Not specified | 596 (15) | 407 (16) | 189 (14) | 0.102 |
 Other specialty | 216 (5) | 123 (5) | 93 (7) | 0.008 |
 OB/GYN | 2 (1) | 1 (0) | 1 (1) | 0.648 |
Baseline A1C results available, n | 1295 | 857 | 438 | Â |
Baseline A1C, mean (SD) | 8.68 (1.8) | 8.72 (1.8) | 8.62 (1.7) | 0.336 |