Table 3 Performance parameters for first trimester HbA1c in screening for gestational diabetes mellitus diagnosed by 1999 WHO criteria in first trimester and throughout pregnancy
From: HbA1c as screening for gestational diabetes mellitus in women with polycystic ovary syndrome
Diagnosis | Cut-off level for HbA1c for dropping OGTT, % (mmol/mol) | Sensitivity, % | Specificity, % | Number of women avoiding OGTT | Number of women avoiding OGTT incorrectly classified |
|---|---|---|---|---|---|
GDM-WHO in first trimester | <4.7 (28) | 100 | 0.5 | 1 | 0 |
<4.8 (29) | 95.0 | 2.4 | 6 | 1 | |
<4.9 (30) | 95.0 | 7.8 | 17 | 1 | |
>5.4 (36) | 30.0 | 93.7 | 19 | 13 | |
>5.5 (37) | 25.0 | 97.6 | 10 | 5 | |
>5.6 (38) | 20.0 | 100 | 4 | 0 | |
GDM-WHO throughout pregnancy | <4.7 (28) | 100 | 0.6 | 1 | 0 |
<4.8 (29) | 98.2 | 2.9 | 6 | 1 | |
<4.9 (30) | 96.4 | 8.7 | 17 | 2 | |
>5.4 (36) | 14.6 | 93.6 | 19 | 11 | |
>5.5 (37) | 9.1 | 97.1 | 10 | 5 | |
>5.6 (38) | 7.3 | 100 | 4 | 0 |