Fig. 5
From: Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet
Analysis of tissue triglyceride, glycogen, and fat mass in MuRF3−/− mice after high fat diet challenge. a Triglyceride analysis of cardiac left ventricle (LV), liver, and skeletal muscle (gastrocnemius). b Glycogen analysis of cardiac LV, liver, and skeletal muscle (gastrocnemius). c Magnetic resonance imaging (MRI) analysis of fat mass, lean body mass, and free water at baseline, 6, 12, and 22 weeks HFD. Values expressed as Mean ± SE. A one-way ANOVA was performed to determine significance of cardiac LV triglyceride and glycogen concentrations, followed by a Holm-Sidak pairwise comparison to determine significance between groups. A Student’s t-test was performed comparing MuRF3−/− vs. MuRF3+/+ groups. Numbers above bars represent number of animals (N) included in each experiment (N = MuRF3+/+, MuRF3−/− in c). n.s. = not significant. *p < 0.001, **p < 0.01, #p < 0.05