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Fig. 3 | BMC Endocrine Disorders

Fig. 3

From: Muscle ring finger-3 protects against diabetic cardiomyopathy induced by a high fat diet

Fig. 3

Histological analysis of cardiac fibrosis. a Cross-sectional analysis of myocytes reveal no differences between MuRF3−/− and wildtype hearts (Masson’s Trichrome). b Objective blinded computer analysis of fibrosis of MuRF3−/− and wildtype hearts after 26 weeks high fat diet reveals no significant differences. c Confocal immunofluorescence analysis of vimentin (fibroblasts) in cardiac cross-sections from MuRF3−/− mice after 26 weeks HFD. Values expressed as Mean ± SE. N = 3 WT and N = 3 MuRF3−/−. A Student’s t-test was performed comparing MuRF3−/− vs. MuRF3+/+ groups. #p < 0.05

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