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Table 3 Clinical characteristics of the subjects of the three sleep quality groups from the results of regression model

From: Poor sleep quality is associated with increased arterial stiffness in Japanese patients with type 2 diabetes mellitus

Variable

Sleep quality group

Unadjusted

Model 1

Model 2

Model 3

Good (n = 462)

Average (n = 185)

Poor (n = 77)

AST (U/L)

21 [18, 27]

21 [18, 26]

22 [18, 27]

1.15

1.30

0.57

-

ALT (U/L)

22 [16,33]

22 [17,33]

25 [17,35]

2.18*

2.00*

1.07

-

γ-GTP (U/L)

25 [17,37]

25 [18,42]

26 [16,42]

0.95

1.40

0.03

-

Uric acid (mg/dl)

5.5 ± 1.2

5.4 ± 1.2

5.4 ± 1.4

−0.86

−0.21

−1.13

-

eGFR (ml/min/1.73 m2)

78 ± 18

79 ± 18

78 ± 19

0.65

-

0.55

-

Total cholesterol (mg/dl)

184 ± 28

188 ± 28

189 ± 25

2.04*

1.66

1.63

-

HDL-C (mg/dl)

59 ± 14

59 ± 14

61 ± 14

0.60

0.47

0.77

-

Triglycerides (mg/dl)

99 [68,150]

102 [72,148]

105 [74,158]

1.23

1.09

0.10

-

Fasting blood glucose (mg/dl)

132 ± 31

136 ± 31

141 ± 32

2.61**

2.41*

1.21

-

HbA1c (%)

6.9 ± 1.0

7.1 ± 1.1

7.1 ± 0.8

2.56*

2.01*

1.38

-

HbA1c (mmol/mol)

51.7 ± 10.6

54.0 ± 11.9

54.1 ± 9.0

2.56*

2.01*

1.38

-

Systolic BP (mmHg)

126 ± 14

127 ± 15

131 ± 13

3.07**

3.06*

1.95

-

Diastolic BP (mmHg)

77 ± 11

77 ± 11

79 ± 12

1.53

1.53

0.61

-

UAE (mg/g creatinine)

10 [6,21]

10 [6,25]

16 [7,40]

2.19*

2.23*

1.25

-

baPWV (cm/s)

1523 [1500, 1547]

1570 [1533, 1606]

1604 [1547, 1661]

-

3.01**

2.79**

2.58*

  1. Data are mean ± SD or median (range: 25 to 75 %). baPWV values are age- and gender-adjusted values (95 % confidence interval)
  2. Unadjusted and Adjusted Ptrend values for linear trends across three groups are based on linear regression analysis for continuous variables or logistic regression analysis for categorical variables. Model 1 and Adjusted Ptrend values for linear trends across three groups are based on linear regression analysis for continuous variables or logistic regression analysis for categorical variables adjusted for age and gender. Model 2 and Adjusted Ptrend values for linear trends across three groups are based on linear regression analysis for continuous variables or logistic regression analysis for categorical variables adjusted for age, gender, BMI, morningness-eveningness questionnaire, Beck Depression inventory, energy intake, alcohol intake, current smoking, and physical activity. Model 3 and Adjusted Ptrend values for linear trends across three groups are based on linear regression analysis for continuous variables adjusted for age, gender, BMI, morningness-eveningness questionnaire, Beck Depression inventory, energy intake, alcohol intake, current smoking, physical activity, systolic BP, HbA1c, total cholesterol, HDL-cholesterol, triglyceride and sleep duration
  3. ALT alanine aminotransferase, AST aspartate aminotransferase, baPWV brachial-ankle pulse wave velocity, BP blood pressure, eGFR estimated glomerular filtration rate, UAE urinary albumin excretion, HDL-C high-density lipoprotein-cholesterol, ɤ-GTP ɤ-glutamyl transpeptidase
  4. *P < 0.05; **P < 0.01; ***P < 0.001