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Table 1 Comparison of demographic and laboratory parameters between the groups

From: Serum macroprolactin levels in pregnancy and association with thyroid autoimmunity

Data

Group 1

Group 2

Group 3

p

Euthyroid

Hypothyroid

Hyperthyroid

(n = 40)

(n = 54)

(n = 44)

Age (years)

29.2 ± 5.6

29.0 ± 5.1

29.3 ± 4.9

NS

Mean number of pregnancies

2.2

2.4

2.7

NS

Number of patients with history of complicated pregnancy (n)

12

18

14

NS

Weight (kg)

69.9 ± 13.9

68.7 ± 14.5

60.7 ± 11.5a,b

<0.005

SBP (mmHg)

111.5 ± 12.5

111.7 ± 11.9

130.5 ± 13.7

NS

DBP (mmHg)

73.2 ± 8.9

72.3 ± 9.1

71.4 ± 10.7

NS

TSH(μIU/L)

1.04 ± 0.7

6.7 ± 10.7a,c

0.02 ± 0.02

<0.001

FT4(ng/dL)

1.13 ± 0.21

1.17 ± 0.54

1.7 ± 0.80a,b

<0.001

FT3 (pg/mL)

2.93 ± 0.33

2.78 ± 0.53

4.84 ± 2.04a,b

<0.001

TPOAb (U/mL)

189.9 ± 352.6

563.8 ± 576.5c

158.8 ± 308.8

<0.001

TGAb(U/mL)

71.1 ± 111.5

164.7 ± 159.0c

123.7 ± 311.2

<0.05

PRL(ng/mL)

57.4 ± 49.4

69.6 ± 74.8

54.7 ± 68.7

NS

macroPRL (n)

1

1

-

NA

monoPRL %

90.6 ± 8.7

91.5 ± 9.2

88.9 ± 10.9

NS

  1. SBP systolic blood pressure, DBP diastolic blood pressure, TSH thyroid stimulating hormone. FT4 free tetraiodotronin, FT3 free triiodotronin, TPOAb thyroid peroxidase antibody, TGAb thyroglobulin antibody, PRL prolactin. monoPRL% the percentage of monomeric prolactin recovery after PEG precipitation
  2. a = group 3 vs group2 p < 0.05; b = group 3 vs group 1 p < 0.001. c = group 2 vs group 1 p < 0.00