Table 1 Baseline patient characteristics for all subjects and each HbA1c target group
Baseline characteristic | All subjects (n = 8,632*) | HbA1c ≤ 6.5% (n = 3,369) | HbA1c > 6.5% to ≤ 7.0% (n = 3,644) | HbA1c > 7.0% to ≤ 7.5% (n = 1,618) | P-values for the comparison of 3 groups |
|---|---|---|---|---|---|
Age (years) | 65.0 (57.0-74.0) | 64.0 (55.0-73.0) | 67.0 (59.0-74.0) | 66.0 (58.0-75.0) | <0.0001 |
Age > 75 years (%) | 19.7 | 17.7 | 20.5 | 22.0 | <0.001 |
Female sex (%) | 45.6 | 46.2 | 45.5 | 44.4 | 0.47 |
BMI (kg/m2) | 31.2 ± 5.9 | 31.1 ± 5.9 | 31.3 ± 5.8 | 31.4 ± 6.0 | 0.38 |
BMI > 30 kg/m2 (%) | 52.0 | 51.3 | 52.1 | 53.1 | 0.47 |
Waist circumference (cm) | 107.6 ± 14.5 | 107.0 ± 15.0 | 108.0 ± 14.0 | 108.0 ± 14.7 | 0.50 |
Current smokers (%) | 11.8 | 11.4 | 12.0 | 11.9 | 0.73 |
Diabetes duration (months) | 67.9 (31.7-117.3) | 55.7 (24.8-100.6) | 75.1 (35.7-122.4) | 82.7 (40.4-131.8) | <0.0001 |
Fasting glucose (mmol/l) | 8.5 ± 2.8 | 7.8 ± 2.6 | 8.8 ± 2.6 | 9.7 ± 3.1 | <0.0001 |
Postprandial glucose (mmol/l) | 10.9 ± 3.4 | 10.0 ± 3.2 | 11.2 ± 3.3 | 12.1 ± 3.7 | <0.0001 |
HbA1c (%) | 7.8 ± 2.1 | 7.2 ± 1.3 | 8.0 ± 2.8 | 8.6 ± 1.5 | <0.0001 |
≤6.5% (%) | 14.7 | 28.9 | 7.1 | 2.0 | <0.0001 |
>6.5% to ≤ 7.0% (%) | 17.4 | 25.6 | 16.2 | 2.5 | <0.0001 |
>7.0% to ≤ 7.5% (%) | 19.8 | 17.7 | 23.1 | 16.8 | <0.0001 |
SBP (mmHg) | 140.3 ± 15.7 | 139.5 ± 15.9 | 140.7 ± 15.5 | 141.3 ± 15.6 | <0.0001 |
DBP (mmHg) | 82.6 ± 9.5 | 82.4 ± 9.8 | 82.7 ± 9.2 | 83.0 ± 9.4 | <0.01 |
HR (beats/min) | 75.0 ± 10.0 | 74.7 ± 10.4 | 75.0 ± 9.4 | 75.9 ± 10.5 | <0.0001 |