Figure 5
From: AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle
Effects of AMPD1 deficiency on gene expression of downstream targets of p70 S6 kinase in skeletal muscle. mRNA expression of PGC1α and β was quantified by real-time PCR using RNA extracted from gastrocnemius muscle of WT and AMPD1 deficient mice fed with normal chow and high fat diet (n = 5 for each group). The mRNA expression levels were normalized with respect to β-actin expression. Data shown are mean ± SD expressed relative to that of WT mice fed with normal chow.