Table 1 Percent blood glucose reduction (Mean ± SEM) with L-ascorbic acid/ tolbutamide / L-ascorbic acid + tolbutamide in normal rats (n= 5)
Time in hours | L-ascorbic acid 60 mg/kg bd.wt. | Tolbutamide 20 mg/kg bd.wt. | L-ascorbic acid 60 mg/kg bd.wt. + Tolbutamide 20 mg/kg bd.wt. |
|---|---|---|---|
0 | - | - | - |
0.5 | 50.91 ± 0.49 | 10.08 ± 1.08 | 53.57 ± 2.01*** |
1 | 20.26 ± 3.14 | 15.56 ± 1.48 | 28.70 ± 1.75*** |
1.5 | 6.06 ± 1.3 | 18.75 ± 2.1 | 23.25 ± 1.72 |
2 | 1.65 ± 0.93 | 22.22 ± 2.13 | 29.78 ± 2.57 |
4 | -2.83 ± 0.4 | 33.0 ± 0.69 | 45.21 ± 2.79** |
6 | - | 10.28 ± 1.02 | 12.54 ± 2.5 |