Figure 8
From: Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH
DMA increases cytoplasmic and mitochondrial NAD(P)H production: Islets were placed in basal KRBH with or without 40 μM DMA. NAD(P)H auto-fluorescence in cytoplasmic (A) and mitochondrial (B) regions was measured by TPEM before and after addition of 16.7 mM glucose or 20 mM αKIC. A. n = 6; * = p < 0.001, compared to same condition without DMA. B. n = 6 ; * = p < 0.05, compared to same condition without DMA.