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Table 3 Exploration of seasonal clustering in 196 patients with type 1 diabetes

From: Depression, smoking, physical inactivity and season independently associated with midnight salivary cortisol in type 1 diabetes

 

Seasons

Spring1(n = 79)

Summer2(n = 50)

Autumn/winter3(n = 67)

P4

MSC

nmol/L

6.7 (4.7, 9.3)

4.6 (2.8, 6.8)

3.5 (2.7, 5.5)

<0.0015

MSC ≥9.3 nmol/L

Yes

20 (25)

9 (18)

5 (8)

0.013

No

59 (75)

41 (82)

62 (92)

Age (years)

 

45.0 (32.0, 52.0)

40.0 (28.0, 48.2)

44.0 (32.0, 53.0)

0.0905

Physical inactivity6

Yes

9 (12)

7 (15)

3 (5)

0.21

No

66 (88)

41 (85)

58 (95)

Gender

Men

39 (49)

32 (64)

35 (49)

0.25

Women

40 (51)

18 (36)

32 (51)

High HbA1c7

Yes

23 (29)

15 (30)

12 (18)

0.21

No

56 (71)

35 (70)

55 (82)

HbA1c

mmol/mol

63 (53, 71)

64 (55, 72)

60 (53, 68)

0.325

%

7.9 (7.0, 8.6)

8.0 (7.2, 8.8)

7.7 (7.0, 8.4)

Smoking8

Yes

9 (12)

4 (8)

3 (5)

0.32

No

66 (88)

45 (92)

59 (95)

Depression9

Yes

11 (14)

4 (8)

5 (8)

0.41

No

68 (86)

46 (92)

62 (92)

  1. Data are n (%) or median (q1, q3). 1(29/03/2009–31/05/2009). 2(01/06/2009–31/08/2009). 3(01/09/2009–18/01/2010). 4Fisher’s exact test unless otherwise indicated. 5Kruskal-Wallis test. 6Physical inactivity: 12 missing values. 7HbA1c >70 mmol/mol (>8.6%). 8Smoking: 10 missing values. 9Self-reported.