Table 3 Proportion of subjects correctly classified by each index using clamp-derived M thirds as reference insulin sensitivity categories
Men | Women | All subjects | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Insulin sensitivity category | Low | Medium | High | Total | Kappa (95% CI) | Low | Medium | High | Total | Kappa (95% CI) | Low | Medium | High | Total | Kappa (95% CI) |
Using clamp as reference | N = 15 | N = 16 | N = 16 | N = 47 | N = 10 | N = 11 | N = 11 | N = 32 | N = 25 | N = 27 | N = 27 | N = 79 | |||
Fasting plasma insulin | 20% | 44% | 25% | 14/47 | −0.05 (−0.25 to 0.14) | 30% | 36% | 9% | 8/32 | −0.13 (−0.33 to 0.10) | 24% | 41% | 18% | 22/79 | −0.08 (−0.22 to 0.08) |
Glucose/Insulin ratio | 53% | 56% | 50% | 25/47 | 0.30 (0.08 to 0.51) | 50% | 45% | 45% | 15/32 | 0.20 (−0.08 to 0.47) | 52% | 52% | 48% | 40/79 | 0.26 (0.09 to 0.42) |
HOMA-IR | 20% | 37% | 19% | 12/47 | −0.12 (−0.30 to 0.06) | 20% | 45% | 18% | 9/32 | −0.08 (−0.31 to 0.15) | 20% | 41% | 18% | 21/79 | −0.10 (−0.24 to 0.04) |
FIRI | 20% | 37% | 19% | 12/47 | −0.12 (−0.30 to 0.08) | 20% | 45% | 18% | 9/32 | −0.08 (−0.30 to 0.16) | 20% | 41% | 18% | 21/79 | −0.10 (−0.24 to 0.04) |
QUICKI | 53% | 50% | 50% | 24/47 | 0.27 (0.05 to 0.46) | 50% | 36% | 54% | 15/32 | 0.20 (−0.04 to 0.47) | 52% | 44% | 52% | 39/79 | 0.24 (0.09 to 0.42) |
Age | 27% | 9% | 56% | 15/47 | −0.02 (−0.22 to 0.18) | 10% | 45% | 27% | 9/32 | −0.08 (−0.32 to 0.16) | 20% | 26% | 44% | 24/79 | −0.04 (−0.19 to 0.11) |
BMI | 53% | 56% | 62% | 27/47 | 0.36 (0.14 to 0.58) | 50% | 27% | 27% | 11/32 | 0.01 (−0.23 to 0.25) | 52% | 44% | 48% | 38/79 | 0.22 (0.05 to 0.38) |
Waist | 53% | 31% | 56% | 21/47 | 0.20 (−0.02 to 0.40) | 50% | 27% | 18% | 10/32 | −0.03 (−0.26 to 0.22) | 52% | 30% | 41% | 32/79 | 0.11 (−0.06 to 0.27) |
WHtR | 53% | 31% | 62% | 25/47 | 0.23 (0.01 to 0.43) | 50% | 36% | 18% | 11/32 | 0.01 (−0.22 to 0.25) | 52% | 33% | 44% | 34/79 | 0.14 (−0.02 to 0.31) |