Table 2 Correlation of CgA levels with clinicopathological features in patients with PNETs and insulinomas

Gender

Male, n = 36

67.9 (46.1-9020.7)

0.394

Female, n = 53

67.2 (25.0-4572.3)

Age (years)

≤48, n = 49

64.8 (25.0-5772.5)

0.039

>48, n = 38

81.2 (26.9-9020.7)

Primary tumor location on pancreas

Head/neck, n = 41

62.5 (25.0-5772.5)

0.019

Body/tail, n = 36

81.9 (45.7-9020.7)

Tumor size (cm)

n = 82, 0.8 - 8,

67.0 (25.0-9020.7)

0.545

r = 0.068,

Grade

G1, n = 37

67.3 (33.9-811.9)

0.103

G2, n = 15

74.3 (26.9-1931.1)

G3, n = 2

323.7 (244.4-403.0)

Stage

I, n = 39

67.2 (25.0-137.2)

0.003

II, n = 22

61.6 (51.2-241.7)

III, n = 5

244.4 (26.9-811.9)

IV, n = 18

302.8 (45.7-9020.7)

Clinicopathological features of patients with insulinomas

CgA levels (ng/ml) median (range)

P value

Gender

Male, n = 25

66.8 (46.1-164.2)

0.072

Female, n = 32

62.6 (25.0-122.0)

Age (years)

≤48, n = 32

61.4 (25.0-164.2)

0.003

>48, n = 25

73.3 (51.2-137.2)

Primary tumor location on pancreas

Head/neck

61.9 (25.0-122.0)

0.009

n = 30

Body/tail

68.9 (51.2-164.2)

n = 26

Tumor size (cm)

n = 56, 0.8 - 4,

64.3 (25.0-164.2)

0.942

r = 0.01

Grade

G1, n = 31

64.8 (33.9-164.2)

0.795

G2, n = 4

62.5 (57.9-104.4)

Stage

Stage I, n = 39

67.2 (25.0-137.2)

0.215

Stage II, n = 15

61.6 (51.2-164.2)