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Table 1 Clinicopathological characteristics of PNET patients

From: Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas

Clinicopathological features of patients with PNETs

Number

Gender n = 89 (%)

Male

36 (40.4)

 

Female

53 (59.6)

 

Male : Female

1:1.47

Age (years) at diagnosis, n = 87

Median (range)

47 (16–74)

PNET subtype n = 89 (%)

Insulinoma

57 (64.0)

 

Non-insulinoma

32 (36.0)

 

NF

19 (21.3)

 

gastrinoma

8 (9.0)

 

glucagonoma

4 (4.5)

 

VIPoma

1 (1.1)

Inherited or sporadic PNETs, n = 89 (%)

Sporadic

86 (96.6)

 

MEN-1 associated

3 (3.4)

Surgery or not, n = 89 (%)

Resection

73 (82.0)

 

Unresection

16 (18.0)

Primary tumor location, n = 77 (%)

Pancreatic head/neck

40 (51.9)

 

Pancreatic body/tail

36 (46.8)

 

duodenum

1 (1.3)

Tumor size (cm) median (range) n = 82

 

1.6 (0.8-8)

 

Insulinoma n = 56

1.5 (0.8-4)

 

Non-insulinoma n = 26

4.3 (1.5-8)

Metastasis or not, n = 83 (%)

No

65 (78.3)

 

Yes

18 (21.7)

Grade, n = 54 (%)

G1

37 (68.5)

 

G2

15 (27.8)

 

G3

2 (3.7)

Stage, n = 84 (%)

I

39 (46.4)

 

II

22 (26.2)

 

III

5 (6.0)

 

IV

18 (21.4)

Clinicopathological features of patients with insulinomas

Number

Gender n = 57 (%)

Male

25 (43.9)

 

Female

32 (56.1)

 

Male : Female

1:1.28

Age (years) at diagnosis, n = 57

Median (range)

47 (16–74)

Inherited or sporadic PNETs, n = 57 (%)

Sporadic

55 (96.5)

 

MEN-1 associated

2 (3.5)

Surgery or not, n = 57 (%)

Resection

54 (94.7)

 

Unresection

3 (5.3)

Primary tumor location, n = 56 (%)

Pancreatic head/neck

30 (53.6)

 

Pancreatic body/tail

26 (46.4)

Tumor size (cm) median (range) n = 56

 

1.5 (0.8-4)

Metastasis or not, n = 57 (%)

No

56 (98.2)

 

Yes

1 (1.8)

Grade, n = 35 (%)

G1

31 (88.6)

 

G2

4 (11.4)