Table 1 Clinical and biochemical features in a girl with phenylketonuria presenting with sexual precocity aged 3 years
From: Central precocious puberty in a 3 year-old girl with Phenylketonuria: a rare association?
Age | 3.2 yr | 3.9 yr | 4.2 yr | 4.6 yr |
|---|---|---|---|---|
Height, cm | 98.8 (0.8) | 107.5 (1.5) | 109.7 (1.4) | 111 (1.2) |
Weight, Kg | 16.1 (0.8) | 18.54 (1.1) | 18.76 (0.9) | 19.44 (0.8) |
BMI, Kg/m2 | 16.43 (0.4) | 16.0 (0.2) | 15.6 (0.0) | 15.7 (0.1) |
MPH, cm | 156.0 (−1.2) | |||
Ht corrected for MPH, SDS | 2.0 | 2.7 | 2.6 | 2.4 |
Bone age, yr | 4.62 | - | 5.37 | - |
Ht velocity, cm/y | 14.3 (5.3) | 10.6 (2.9) | 7.1 (0.1) | 4.3 (−2.2) |
Pubertal status | B4,P2,A1 | B2,P2,A1 | B1–2,P1, A1 | B1–2,P1, A1 |
Basal/Peak LH, U/l | 1.9/33.1 | |||
Basal/Peak FSH, U/l | 2.4/6.5 | |||
Triptorelin dose | 11.25 mg/12 weeks | 11.25 mg/10 weeks | 11.25 mg/10 weeks | 11.25 mg/10 weeks |