Contribution of SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study

Table 1 Demographic and biochemical characterizations of participants

Demography and biochemical profiles		Normal control	GADA negative diabetes
Demography and biochemical profiles		n = 620	n = 1107
Gender %	Male/female	61.6/38.4	67.6/32.4
Races %	Malay	41.0	38.4
	Chinese	32.9	26.5
	Indian	26.1	35.1
Age (years)		49.5(48.6–50.3)	51.3(50.8–51.9)
P- value			*0.001*
Body mass index (kg/m²)		24.6(24.3–25.0)	27.4(27.1–27.7)
P- value			*<0.001*
Waist circumference (cm)		85.2(84.2–86.2)	96.1(95.4–96.8)
P- value			*<0.001*
Systolic blood pressure (mmHg)		128(127–130)	134(133–135)
P- value			*<0.001*
Diastolic blood pressure (mmHg)		80(79–80)	81(80–82)
P- value			*0.005*
Fasting plasma glucose (mmol/l)		4.98(4.94–5.02)	7.89(7.73–8.05)
P- value			*<0.001*
Fasting plasma insulin (pmol/l)		59.65(56.35–63.15)	98.15(94.08–102.39)
P- value			*<0.001*
HOMA-β		111.35(107.19–115.67)	70.84(67.41–74.44)
P- value			*<0.001*
HOMA-IR		1.27(1.20–1.35)	2.45(2.34–2.55)
P- value			*<0.001*
High density lipoprotein (mmol/l)		1.34(1.32–1.37)	1.09(1.07–1.10)
P- value			*<0.001*
Triglyceride (mmol/l)		1.13(1.09-1.17)	1.58(1.53–1.63)
P- value			*<0.001*

The results presented represent geometric means (95% confidence interval of the mean), which evaluated by ANOVA. Bolded values are significant. GADA: glutamic acid decarboxylase antibodies.

ISSN: 1472-6823