Significant reduction of HbA1c during the 12-week exercise game intervention. Shown are means ± standard error of means. (A) HbA1c values have been determined at baseline and after 12 weeks in the intervention group (n = 93; white bars) and the control group (n = 83; checked bars) as well as after additional 12 weeks of intervention (n = 54). (B) Differences in HbA1c were defined as values after 12 weeks of intervention or waiting minus baseline values, and additionally for the control group, values after 12 weeks of intervention minus values after 12 weeks of waiting. Differences between groups have been estimated using the Mann–Whitney test and within groups using the Wilcoxon signed rank test; Wilcoxon signed rank test was used to determine if differences were significantly different from 0 (*, p < 0.05; **, p < 0.01; ***, p < 0.001).