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Table 1 Summary of reports (sorted by sample size) on HOMA-IR cut-off in different populations

From: Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study

Study Characteristics of study population Threshold value Criteria
Hedblad, 2000 [15] N = 4,816 Sweden, population-based sample ≥ 2.0 75th percentile
Summer, 2008 [16] N = 2804, U.S. NHANES population, age ≥ 20 yr., normal BMI and fasting glucose ≥2.73 66th percentile
Geloneze, 2006 [17] N = 1317 Brazilian, age: 40 ± 12 yr, BMI: 34 ± 10 kg/m2 ≥ 2.77 90th percentile
Esteghamati, 2009 [18] N = 1,276 Iranian, ≥1.80 ROC
Age: 38 ± 12 yr, non-diabetic, normotensive ≥1.95 ROC
IDF-MetS ≥1.6 75th percentile
ATPIII-MetS ≥1.8 80th percentile
  ≥ 2.3 90th percentile
Marques-Vidal, 2002 [19] N = 1153, France, age: 35–64 yr, population based sample ≥3.8 75th percentile
Do, 2010 [20] N = 738 Thailand, age: ≥35 yr, normal BMI and fasting glucose 1.55 90th percentile
Miccoli, 2005 [38] N = 225 Italian, age: 40–79 yr, healthy subjects ≥ 2.77 80th percentile
Nakai, 2002 [22] N = 161 Japanese, age: 41.6 ± 0.4 yr, healthy subjects ≥ 1.7 90th percentile
Ascaso, 2001 [39] N = 140 Spanish, age: 7–16 yr 3 ROC
Tome, 2009 [40] N = 2860 Spanish, population based age: 18–104 yr, BMI: 26.2 ± 4.9 kg/m2 2 ROC