Combining glycosylated hemoglobin A1c and fasting plasma glucose for diagnosis of type 2 diabetes in Chinese adults

Table 3 Performance of FPG, 2hPG and HbA1c alone and combining use of FPG (mmol/l) and HbA1c (mmol/mol) in diagnosing diabetes

Population	Subjects	Diabetes	Se (%)	Sp (%)	PPV	NPV
Individual test
By FPG alone^a	6,661	239	52.6	100.0	100.0	96.7
By 2hPG alone^b	6,422	215	100.0	100.0	100.0	100.0
By HbA1c alone^c	6,661	343	75.6	89.3	34.1	98.0
Combining use of FPG and HbA_1c
All subjects	6,661	380	83.7	89.3	36.4	98.0
Subjects with elevated WC^d	2,810	239	83.0	85.8	39.8	97.8
Subjects with elevated TG^e	2,385	269	87.4	85.1	42.7	98.2
Subjects with HW^f	1,320	162	86.6	82.9	45.5	97.4

^aFPG ≥ 7.0 mmol/l; ^b2 hPG ≥ 11.1 mmol/l; ^cHbA_1c ≥ 43 mmol/mol (6.1%); ^dWC ≥ 90 cm in men, ≥ 80 cm in women; ^eTG ≥ 1.695 mmol/l; ^fhypertriglyceridemic waist phenotype, defined as having both a high WC (≥ 90 cm for men, ≥ 80 cm for women) and an elevated TG level (≥ 1.695 mmol/l).

ISSN: 1472-6823