Table 2 Performance of the optimal HbA 1c cut-points in participants by demographic and clinical characteristics
Characteristics | Sensitivity of FPG ≥ 7.0 mmol/l (%) | Optimal HbA1cmmol/mol (%) | Performance of optimal HbA1cvalue (%) | |||
|---|---|---|---|---|---|---|
Sensitivity | Specificity | PPV | NPV | |||
All subjects | 52.6 | 43 (6.1) | 75.6 | 89.3 | 34.1 | 98.0 |
Gender | ||||||
Male | 59.0 | 43 (6.1) | 78.2 | 88.8 | 36.7 | 98.0 |
Female | 45.9 | 43 (6.1) | 72.7 | 89.8 | 31.6 | 98.1 |
Age | ||||||
35-44 | 68.8 | 40 (5.8) | 84.4 | 84.9 | 15.1 | 99.4 |
45-54 | 59.9 | 41 (5.9) | 85.9 | 82.5 | 23.5 | 98.9 |
55-64 | 51.1 | 42 (6.0) | 82.2 | 81.3 | 27.3 | 98.2 |
65-74 | 40.0 | 45 (6.3) | 70.0 | 91.9 | 51.1 | 96.2 |
BMI | ||||||
≤23.0 | 52.9 | 43 (6.1) | 73.6 | 92.7 | 27.0 | 99.0 |
23.1-24.9 | 58.0 | 43 (6.1) | 75.0 | 90.1 | 32.9 | 98.2 |
≥25.0 | 50.6 | 43 (6.1) | 76.4 | 85.3 | 37.8 | 96.9 |
Elevated WCa | ||||||
No | 56.6 | 43 (6.1) | 78.9 | 91.8 | 30.2 | 99.0 |
Yes | 50.4 | 43 (6.1) | 73.6 | 85.8 | 37.1 | 96.6 |
Hypertensionb | ||||||
No | 52.6 | 43 (6.1) | 76.3 | 90.6 | 29.7 | 98.7 |
Yes | 52.7 | 43 (6.1) | 74.6 | 84.5 | 42.1 | 95.7 |
Elevated TGc | ||||||
No | 50.8 | 41 (5.9) | 83.2 | 83.1 | 18.3 | 99.1 |
Yes | 53.9 | 43 (6.1) | 78.1 | 85.1 | 39.9 | 96.8 |
Reduced HDL-Cd | ||||||
No | 56.7 | 43 (6.1) | 72.7 | 89.6 | 31.6 | 98.0 |
Yes | 46.4 | 43 (6.1) | 79.9 | 88.7 | 38.4 | 98.0 |
HW phenotypee | ||||||
No | 53.2 | 43 (6.1) | 75.3 | 90.8 | 30.0 | 98.6 |
Yes | 51.9 | 43 (6.1) | 75.9 | 82.9 | 42.3 | 95.4 |