Figure 1

Kaplan-Meier survival curves and hazard ratios for retinopathy in the DCCT dataset according to LPA (data is categorised according to Standard / Intensive treatment arm, and Primary / Secondary prevention cohort). Data is categorised according to Standard / Intensive treatment arm, and Primary / Secondary prevention cohort and each curve is stratified according to the three categories of Metabolic Equivalent of Tasks. Panel A shows the primary cohort in the Intensive arm, Panel B shows the primary cohort in the standard treatment arm, Panel C shows the secondary cohort in the intensive treatment arm and Panel D shows the secondary cohort in the standard treatment arm. Both the survival curves in panels A and C show a higher cumulative survival rate when compared to the survival graphs in Panel B and D. However, Kaplan-Meier analysis of the survival graphs did not demonstrate any difference in progression of retinopathy in the three incremental physical activity categories in either the intensive or standard treatment arm. Log-rank test for the intensive arm Chi2 is 3.14 (P=0.21) and Log-rank test for the standard treatment arm Chi2 is 0.93 (P=0.63). Separation in the curves seen towards the end of the graphs is indicative of the fewer numbers followed up for a longer period.