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Table 4 Regression analyses of ghrelin with BMD and Z-scores in women based on menopausal status 1

From: Beneficial association of serum ghrelin and peptide YY with bone mineral density in the Newfoundland population

 

Pre-menopausal (N = 971)

Post-menopausal (N = 653)

 

Variables

β*

(95% CI)

P

R2

Variables

β

(95% CI)

P

R2

L2-L4 BMD

BMI

0.005

(0.003, 0.006)

<0.001

0.05

BMI

0.006

(0.003, 0.008)

<0.001

0.088

 

Smoking

−0.032

(−0.059, −0.004)

0.023

 

Smoking

−0.055

(−0.092, −0.017)

0.005

 
      

Age

−0.002

(−0.004, −0.001)

0.001

 
      

Ghrelin

0.014

(0.001, 0.027)

0.037

 

Femoral Neck BMD

BMI

0.008

(0.006, 0.010)

<0.001

0.139

Age

−0.004

(−0.006, −0.003)

<0.001

0.195

 

Age

−0.003

(−0.004, −0.002)

<0.001

 

BMI

0.007

(0.005, 0.009)

<0.001

 
 

PA2

0.013

(0.007, 0.019)

<0.001

 

Smoking

−0.044

(−0.077, −0.012)

.007

 
 

Smoking

−0.039

(−0.067, −0.010)

0.007

 

PA

0.008

(0.001, 0.015)

.019

 

Total Hip BMD

BMI

0.01

(0.008, 0.011)

<0.001

0.164

BMI

0.011

(0.009, 0.013)

<0.001

0.263

 

PA

0.014

(0.008, 0.019)

<0.001

 

Age

−0.003

(−0.004, −0.002)

<0.001

 
 

Smoking

−0.034

(−0.063, −0.006)

0.017

 

Smoking

−0.041

(−0.071, −0.011)

0.008

 

L2-L4 Z-score

Smoking

−0.394

(−0.673, −0.116)

0.006

0.012

Smoking

−0.596

(−0.964, −0.229)

0.002

0.034

      

Ghrelin

0.135

(0.006, 0.263)

0.04

 

Femoral Neck Z-score

PA

0.106

(0.058, 0.154)

<0.001

0.051

Smoking

−0.421

(−0.658, −0.185)

.001

0.025

 

Smoking

−0.304

(−0.538, −0.071)

0.011

      
 

BMI

0.018

(0.003, 0.033)

0.018

      
 

Ghrelin

0.096

(0.017, 0.175)

0.018

      

Total Hip Z-score

BMI

0.043

(0.028, 0.058)

<0.001

0.083

BMI

0.043

(0.029, 0.057)

<0.001

0.084

 

PA

0.092

(0.044, 0.140)

<0.001

 

Smoking

−0.32

(−0.552, −0.089)

0.007

 
 

Smoking

−0.315

(−0.546, −0.085)

0.007

      
 

Ghrelin

0.107

(0.029, 0.185)

0.008

      
  1. 1Regression model adjusted for age, BMI, alcohol consumption, physical activity, and smoking2 Physical Activity* Unstandardized β coefficients 95% Confidence Interval.