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Table 3 Regression analyses of ghrelin with BMD and Z-scores in women and men 1

From: Beneficial association of serum ghrelin and peptide YY with bone mineral density in the Newfoundland population

 

Female

Male

 

Variables

β

(95% CI)

P

R2

Variables

β

(95% CI)

P

R2

L2-L4 BMD

Age

−0.003

(−0.003, −0.002)

<0.001

0.1

BMI

0.006

(0.003, 0.009)

<0.001

0.045

 

BMI

0.005

(0.004, 0.007)

<0.001

 

Age

−0.001

(−0.002, 0.000)

0.012

 
 

Smoking

−0.043

(−0.065, −0.021)

<0.001

      
 

Ghrelin

0.009

(0.002, 0.017)

0.015

      

Femoral Neck BMD

Age

−0.004

(−0.005, −0.004)

<0.001

0.238

Age

−.006

(−0.006, −0.005)

<0.001

0.361

 

BMI

0.008

(0.006, 0.009)

<0.001

 

BMI

.012

(0.010, 0.015)

<0.001

 
 

PA2

0.011

(0.007, 0.016)

<0.001

 

PA

.015

(0.007, 0.023)

<0.001

 
 

Smoking

−0.044

(−0.065, −0.023)

<0.001

 

Smoking

−.047

(−0.083, −0.010)

0.012

 
 

Ghrelin

0.008

(0.000, 0.015)

0.04

 

Alcohol

.001

(0.000, 0.002)

0.020

 

Total Hip BMD

BMI

0.011

(0.009, 0.012)

<0.001

0.234

BMI

.013

(0.011, 0.016)

<0.001

0.247

 

Age

−0.003

(−0.003, −0.002)

<0.001

 

Age

−.002

(−0.003, −0.001)

<0.001

 
 

PA

0.009

(0.005, 0.014)

<0.001

 

PA

.013

(0.005, 0.020)

0.002

 
 

Smoking

−0.036

(−0.057, −0.016)

<0.001

 

Alcohol

.001

(0.000, 0.002)

0.019

 
 

Ghrelin

0.009

(0.002, 0.016)

0.009

 

Smoking

−.037

(−0.072, −0.002)

0.036

 

L2-L4 Z-score

Smoking

−0.458

(−0.675, −0.241)

<0.001

0.022

     
 

Ghrelin

0.102

(0.027, 0.177)

0.007

      

Femoral Neck Z-score

Smoking

−0.338

(−0.502, −0.173)

<0.001

0.04

PA

0.158

(0.092, 0.224)

<0.001

0.085

 

PA

0.078

(0.044, 0.113)

<0.001

 

BMI

0.055

(0.031, 0.079)

<0.001

 
 

Ghrelin

0.073

(0.015, 0.131)

0.013

      
 

BMI

0.013

(0.003, 0.024)

0.015

      

Total Hip Z-score

BMI

0.043

(0.033, 0.053)

<0.001

0.076

BMI

0.08

(0.058, 0.102)

<0.001

0.137

 

Smoking

−0.286

(−0.447, −0.125)

0.001

 

PA

0.122

(0.059, 0.185)

<0.001

 
 

PA

0.059

(0.026, 0.093)

0.001

 

Alcohol

0.007

(0.000, 0.015)

0.042

 
 

Ghrelin

0.081

(0.024, 0.137)

0.005

      
  1. 1Regression model adjusted for age, BMI, alcohol consumption, physical activity, and smoking2 Physical Activity* Unstandardized β coefficients 95% Confidence Interval.