Table 5 Mean on-treatment changes in A1C (stratified analyses)
From: Real-world utilization patterns and outcomes of colesevelam hcl in the ge electronic medical record
Stratum | LOCF within day window | Target day | Actual day | N | A1C (%) | ||
|---|---|---|---|---|---|---|---|
Mean | Baseline mean | Post mean | Change mean (95% CI) | ||||
Week 16 | 42 – 140 | 112 | |||||
Monotherapy | 96.5 | 239 | 7.89 | 7.51 | −0.38 (−0.49, -0.27) | ||
Augment/Switch | 96.0 | 448 | 8.24 | 7.80 | −0.44 (−0.55, -0.33) | ||
New Combination | 96.1 | 151 | 8.66 | 7.63 | −1.03 (−1.31, -0.75) | ||
Week 26 | 42 – 210 | 182 | |||||
Monotherapy | 141.5 | 268 | 7.90 | 7.55 | −0.35 (−0.46, -0.24) | ||
Augment/Switch | 143.7 | 511 | 8.28 | 7.87 | −0.40 (−0.51, -0.29) | ||
New Combination | 139.3 | 183 | 8.69 | 7.51 | −1.18 (−1.46, -0.90) | ||
Week 52 | 42 – 395 | 365 | |||||
Monotherapy | 283.7 | 188 | 7.83 | 7.40 | −0.43 (−0.59, -0.27) | ||
Augment/Switch | 289.2 | 439 | 8.29 | 7.84 | −0.45 (−0.57, -0.33) | ||
New Combination | 288.3 | 222 | 8.55 | 7.52 | −1.03 (−1.26, -0.80) | ||